The first test is a new technology using CRISPR. The second RT-PCR test uses the existing standard method for doing molecular diagnostics. It’s not some groundbreaking new thing
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Not negating that RT-PCR team’s efforts but designing primers and a PCR assay is...not new.
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The second test had “perfect” sensitivity. Perfect is not a quantifiable metric. What does that even mean? That it’s very sensitive? Because the paper measures that by diluting the template, and it’s consistent with what you’d expect for RT-PCR. It’s fine, not “perfect”
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And 100% specificity? The second test was only validated in a tiny cohort (pos n=2, neg n=31), no wonder there weren’t false positives. That’s not even remotely in the realm of statistical power you’d need to validate something for clinical use.
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The problem with getting information from an “expert” who evidently knows approximately zero about molecular assays is that these both are presented like
#nCoV2019 tests coming soon to a clinic near you! Nope. Neither test is ready for use as the diagnostic.Prikaži ovu nit -
And the last thing anyone anywhere needs is a bunch of people overwhelming providers with demands for tests that are either unproven technology not yet evaluated in patients or some primers that haven’t been adequately validated for clinical use
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https://scholar.harvard.edu/ericding He's an epi & prof at Harvard SPH w/ 150 pubs & 60k citations... Maybe he doesn't focus on virology, but he's far from a layperson. You should consider making these valuable points w/o character assassination, or you lose cred too.
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It isn’t character assassination to oppose an unqualified person. making false statements that can directly harm people. It is dangerous to speak with authority on things you know nothing about during a public health crisis. I wouldn’t claim expertise in nutrition during a famine
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As someone who works in a public health lab doing RT-PCR viral diagnostics all day... just wow. Those tweets are so bad they're basically nonsensical. And given what we know about nCoV 2019 at this time impossible to verify.
Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi
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Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi
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