I've been told that my woes may be about large window server display buffers and to try 10.10.2 beta. Giving it a shot…
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10.10.2 was a nightmare for my rMBP.. had to rollback to to 10.10.1…
Lots of graphics issues btw
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YMMV - mine is a late 2013 rMBP w NVIDIA GeForce GT 750m.
Had issues opening PNGs, Photoshop, Safari, etc.