The design agency Bureau has been working on a fascinating format for ebooks, trying for the benefits of high-craft fixed page layout in a scroll-driven, flexible-layout context.
Essay on their format (videos 2/3 through): bureau.rocks/books/manifest
Demo:
Conversation
Have you read things by ?
I really enjoyed his Typography for lawyers, and I was impressed he wrote his own software to produce his books:
docs.racket-lang.org/pollen/
Practical Typography is probably the best place to start.
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Yes, of course! These books are quite lovely, and in many senses more "native" to what the web "wants."