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__ice9's profile
ice9
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@__ice9

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ice9

@__ice9

I do quantitative things. Sometimes I think about society and economics.

Chicago, IL
Joined January 2017

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    1. ice9‏ @__ice9 20 Apr 2020

      Recent research indicates that different strains of the novel coronavirus SARS-CoV-2 do indeed have meaningful differences in pathogenicity. This was difficult to confirm previously. SCMP summary article: https://www.scmp.com/news/china/science/article/3080771/coronavirus-mutations-affect-deadliness-strains-chinese-study … Original preprint: https://www.medrxiv.org/content/10.1101/2020.04.14.20060160v1 …pic.twitter.com/V9nGRIgmyp

      20 replies 122 retweets 248 likes
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    2. ice9‏ @__ice9 20 Apr 2020

      The extent to which strain virulence differences may explain regional variation in case growth and outcomes is not yet clear, but it is very suggestive.

      2 replies 5 retweets 42 likes
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      ice9‏ @__ice9 20 Apr 2020

      ice9 Retweeted

      Another useful implication: https://twitter.com/Pharmaheretic/status/1252382829335293952?s=20 …

      ice9 added,

      This Tweet is unavailable.
      4:53 PM - 20 Apr 2020
      • 7 Retweets
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      • inquirer sans frontier JonBownePolitix David Holzman MV Wendy Keeler🌲 Dr. Birep Aygün ~cin Andrija Spotted Toad
      5 replies 7 retweets 53 likes
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        2. ice9‏ @__ice9 20 Apr 2020
          Replying to @SherShahSheroo

          Remains to be determined. If it behaves like other large-scale coronaviruses, that may be possible.

          0 replies 0 retweets 1 like
        3. End of conversation
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        2. Unrecorded Yak‏ @aperfectstrange 20 Apr 2020
          Replying to @__ice9

          “Ability to mutate vastly underestimated” - could you have a more lurid title? So this follows the two strain theory, one mild; one severe....

          1 reply 0 retweets 0 likes
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        1. Fatuous Pauper‏ @basedc1 20 Apr 2020
          Replying to @__ice9

          But if it mutates more, doesn't that mean vaccines won't be as effective?

          0 replies 0 retweets 0 likes
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        1. Prof. Arthur Fonzarreli‏ @chuckdavenav 21 Apr 2020
          Replying to @__ice9

          Excellent idea!

          0 replies 0 retweets 0 likes
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        1. Zoroaster‏ @ZoroasterReborn 21 Apr 2020
          Replying to @__ice9

          Is there a risk of ADE? Could it turn out that people who are infected by a milder strain be at risk if infected later on by a different strain? https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102551/ …

          0 replies 0 retweets 0 likes
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        2. TGGP‏ @TeaGeeGeePea 21 Apr 2020
          Replying to @__ice9

          I recall that one of the objections to @robinhanson on variolation was the importance of strain selection.

          1 reply 0 retweets 0 likes
        3. Robin Hanson‏Verified account @robinhanson 21 Apr 2020
          Replying to @TeaGeeGeePea @__ice9

          That not an objection to deliberate infection, it is a refinement on priorities in trials. We can study dose, strain, and delivery vector. All of them are likely candidates for better infection.

          0 replies 0 retweets 0 likes
        4. End of conversation

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