The pragmatic Dharma group in Portland is full of good people. Tonight I when to a book club on Daniel Ingram's book Mastering the Core Teachings of the Buddha.
The way it's written, it's seems like MTCB represents the POI as a never ending cycle which having begun you can never leave but can find relief at the end before the next cycle.
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The POI section reads a bit like a stream of consciousness medical reference. And it's useful as a reference but it widely diverges from what a single person might expect to experience.
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Like reading WebMD, you could be primed to see things which aren't symptoms as symptoms, except in this case you can catch the disease, so to speak, by believing you have it.
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"Nasty little Buddhist"
Seeking via neuroscience and psychology informed dharma.