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Prikvačeni tweet
Our new paper on drug resistance prediction in TB is out! https://wellcomeopenresearch.org/articles/4-191/v1 … Highlights: a new (reimplemented) tool called Mykrobe, living paper that will have updated benchmarks and resistance catalogue over time, measuring impact of errors on treatment regimen.thread 1/npic.twitter.com/R0hc9eVTXE
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Our vaccine optimisation paper made the Daily Mail! Published today in
@NatureMicrobiol https://rdcu.be/b08N1 . Daily Mail: Deadly infections 'could be HALVED by more specific vaccines' https://mol.im/a/7961729 via@MailOnlineHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Zamin Iqbal proslijedio/la je Tweet
With it we show how you can reach 30x coverage of a 148 gene cancer panel on a single MinION run to yield SV calling 100% concordant to deep coverage ONT or HiFi reads. Crucially, we find twice the number of SVs using long reads compared to short reads in these cancer genes.pic.twitter.com/uJH38Fw0gc
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Introducing "Targeted nanopore sequencing by real-time mapping of raw electrical signal with UNCALLED" with
@samkovaka@timp0 et al. Does selective enrichment and depletion of any targeted genomic region purely in software for@nanopore sequencing.https://www.biorxiv.org/content/10.1101/2020.02.03.931923v1 …Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
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Pick your panel poison, but things get much more interesting from here ..... dynamic assembly and gap filling on the fly ...... nicely done
@mattloose and crew
https://www.biorxiv.org/content/10.1101/2020.02.03.926956v1 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Zamin Iqbal proslijedio/la je TweetHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi
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People talk about public health interventions that are truly effective. Well, roundabouts are a hugely undersung success story. They reduce serious crashes by 78-82%, are more efficient, less costly & more aesthetically appealing than other designs. https://safety.fhwa.dot.gov/intersection/innovative/roundabouts/ …pic.twitter.com/M0VKS4JidM
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This is super interesting. Does kmer size affect the error bound? And for the PWL how does right shifting by b bits give which bin a query belongs to?
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What I have not talked about is assessing diagnostics. This is surprisingly easy - call `plot()` on lm, nlme or merMod objects to see some diagnostic plots. The function `bartlett.test()` can be used for testing for heteroscedasticity.
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I thought it could be helpful to have a thread on ANOVA in R. As a statistical consultant, this is the most frequent FAQ I get from clients - how to run a linear model on their data, conduct hypothesis tests, extract predicted means and perform contrasts.
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As the case numbers grow and challenge surveillance capacity in more places, we need a way to estimate case numbers without testing everyone. We thought thru this in 2009 flu https://www.dropbox.com/s/7wnuqz15leh7x47/2009%20Lancet%20Lipsitch%20maintain%20surveillance.pdf?dl=0 … - this Lancet paper resulted. Please share
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A lot of countries are closing borders and cancelling flights. Might slow the expansion of
#2019nCoV, but not clear that it will stop it completely - here’s a study from a few years ago that looked at this question for pandemic flu:https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.0030212 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
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2. Bad datasets tend to take more time to work with than good ones. This can easily lead to a very bad bottomline on your productivity. Monitor cost-benefit and cut projects accordingly. There is more data, and more ideas, than time.
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Two lessons I've drawn out of this: 1. Good experimental collaborators are essential. They are also hard to find. Once you find one, hold on to them. (Corollary: at least as important as their scientific brilliance is that they are good people.) (2/3)
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Equally true for bioinformatics.https://twitter.com/hspter/status/1223315485128683522 …
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Stepwise evolution and convergent recombination underlie the global dissemination of carbapenemase-producing Escherichia coli. https://rdcu.be/b04eA
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Very pleased I had opportunity to chat with
@CTVNews about the#nCoV#nCoV2019#coronarvirus outbreak. In particular it was great to have the chance to praise the global scientific community response, fast & open data release & sharing!https://www.ctvnews.ca/video?clipId=1889487&playlistId=1.4791826&binId=1.810401&playlistPageNum=1&binPageNum=1 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
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On a day when there was much to be sad about, it was a delight to hear my former PhD student, now Professor Parkhill, give his Inaugural Lecture in Cambridge .pic.twitter.com/cqNP1UaUyr
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A message to Europe, this morning on the White Cliffs of Dover. Sound on.pic.twitter.com/E3VY8BaGjK
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Influenza virus transmission: with or without symptoms, you're dropping Flu virus -a post from 2018. Seems relevant again.https://virologydownunder.com/influenza-virus-transmission-with-or-without-symptoms-youre-dropping-flu-virus/ …
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This
#nCoV2019 case from Bavaria had a sample collected on Jan 28. The full genome of the virus was shared publicly 3 days later on Jan 31. That's the new record. Incredible job@c_drosten@vmcorman@ChariteBerlin

https://twitter.com/nextstrain/status/1223239883650752512 …
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