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Prikvačeni tweet
Our 2nd insula paper is out in
@NeuroCellPress! We found that insular cortex represents current bodily state AND uses external cues to “simulate” future changes to bodily physiology – “How do I feel?” + “How will this make me feel?” More in THREAD…1/7 https://www.cell.com/neuron/fulltext/S0896-6273(19)31093-1?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0896627319310931%3Fshowall%3Dtrue …pic.twitter.com/seX1kbgj6b
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Yoav Livneh proslijedio/la je Tweet
Interested in home-cage behavioral training for mice? The Open Ephys Production Site has started distributing FED3! https://open-ephys.org/fed3/fed3 We worked together over the last 6 months to improve the design of FED3 to be more reliable and functional. (thread)pic.twitter.com/7UNLD3w8gq
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Yoav Livneh proslijedio/la je Tweet
Exciting new research on the insular cortex, neural basis of interoception from
@BIDMChealth labs of@andermann_mark & Brad Lowell, first author@Yoav_Livneh -- basic research that could one day help us better understand eating disorders, obesity, addiction etc.https://twitter.com/BIDMChealth/status/1219723340807454721 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Yoav Livneh proslijedio/la je Tweet
Activity in
#InsularCortex Reflects Current and Future Physiological States New this week in@NeuroCellPress by@andermann_mark,@Yoav_Livneh and colleagues@brainpostco's scientific summary by@stephaniedwill: https://www.brainpost.co/weekly-brainpost/2020/1/21/activity-in-insular-cortex-reflects-current-and-future-physiological-states …pic.twitter.com/u4LVfM3ME3
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Yoav Livneh proslijedio/la je Tweet
The Alhadeff lab is recruiting a postdoc for a funded position to study gut-brain signaling and food intake control! Please RT and share with grad students. Check out our website, http://www.alhadefflab.com , for more info and email/DM me if interested!
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Yoav Livneh proslijedio/la je Tweet
New interoception paper hot off the press from Mark Andermann's group
@andermann_mark@Yoav_Livneh: https://www.cell.com/neuron/fulltext/S0896-6273(19)31093-1?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0896627319310931%3Fshowall%3Dtrue … First, this is a super-cool experiment and methodology. The causal power with manipulating neural circuits related to interoception is unparalleled.Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Yoav Livneh proslijedio/la je Tweet
Making sense of the self: BIDMC researchers demonstrate how the brain assesses and predicts physiological states of the body - read more here: http://bit.ly/2GaE6ph https://twitter.com/Yoav_Livneh/status/1217849999721103368 …
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Yoav Livneh proslijedio/la je Tweet
Trainees (grad-students & PDs), we have more travel awards available - come join us at the
#2020DAC@WeizmannScience! Amazing lineup of speakers, the conference itself is free. Send your abstract until Jan 31, we extended the deadline. Hope to see you there!https://twitter.com/Spiegel_Lab/status/1208327651041193984 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Yoav Livneh proslijedio/la je Tweet
Failure to provide adequate childcare, parental leave and maternity cover ARE FORMS of structural sexism, and greatly harm science. Essential reading.https://twitter.com/fmrib_karla/status/1218561563755413504 …
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Yoav Livneh proslijedio/la je Tweet
This is such an interesting paper. Estimation of Current and Future Physiological States in Insular Cortexhttps://www.cell.com/neuron/fulltext/S0896-6273(19)31093-1#.XiOpJQJ2IaU.twitter …
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Yoav Livneh proslijedio/la je Tweet
After >2 years of effort by our team in 7 labs, we present to you: 3 million choices from 101 mice in a standardized decision-making task.
"A standardized and reproducible method to measure decision-making in mice" https://doi.org/10.1101/2020.01.17.909838 …
Story time! 
1/10pic.twitter.com/WBdJh7A0eb
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Yoav Livneh proslijedio/la je Tweet
Find out about Calcitonin receptor neurons in the NTS! They produce not just satiation but long-term satiety without aversion. Way to go for suppressing feeding without nausea.https://www.cell.com/cell-metabolism/fulltext/S1550-4131(19)30677-1?dgcid=raven_jbs_aip_email …
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Yoav Livneh proslijedio/la je Tweet
Calcitonin Receptor Neurons in the Mouse Nucleus Tractus Solitarius Control Energy Balance via the Non-aversive Suppression of Feedinghttps://www.cell.com/cell-metabolism/pdfExtended/S1550-4131(19)30677-1 …
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Yoav Livneh proslijedio/la je Tweet
New publication alert! Making sense of the self https://eurekalert.org/e/9pdf via
@BIDMCHealth@EurekAlert@Yoav_LivnehHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Thanks to everyone involved in the work and to the many people who took the time to give us insightful feedback. Please DM me if you don't have access to the paper. END 7/7
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We speculate that these cortical “simulations” along different dimensions/axes of population activity serve to guide and prioritize behavior. For example, how will eating salty food when you’re both hungry and thirsty affect energy and fluid balance?…6/7pic.twitter.com/iXK2FKiwoj
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But what do food/water predicting cues actually mean in insular cortex? We looked at the patterns of activity that these cues evoke and found that they drive a transient “simulation” of a future satiety state that would only occur hours later…5/7
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Insular cortex was not “fooled” by the hypothalamus: artificial activation of hypothalamic “hunger neurons” and “thirst neurons” in sated animals restored responses to learned food/water cues. BUT it did NOT affect ongoing activity, which still reflected to true bodily state…4/7
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We followed-up on our previous work (https://www.nature.com/articles/nature22375 …) and imaged insular cortex population activity in hungry or thirsty mice as they gradually became sated. insular ongoing activity patterns reflected current bodily state, not behavioral state (arousal, motivation)… 3/7
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Insula is considered the “primary interoceptive cortex”. It’s hypothesized to integrate visceral-sensory info about current bodily state (hunger,thirst,temperature,etc) with previously learned info to potentially compute interoceptive predictions and prediction errors…2/7
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