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Prikvačeni tweet
1/4 Want to probe over 100 synaptic connections at once? Check out our new paper
@eLife with@FMittermaier on how to set up a multipatch with automated pipette cleaning and how it applies to human cortical slices https://elifesciences.org/articles/48178#neuroscience#sciencetwitter#ephyspic.twitter.com/m5E77tsk6iPrikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Yangfan Peng proslijedio/la je Tweet
50 days free access to our recent article. Happy responsible sharing...
https://authors.elsevier.com/a/1aM841S07cD7s Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Yangfan Peng proslijedio/la je Tweet
Brains are amazing. Our lab demonstrates that single human layer 2/3 neurons can compute the XOR operation. Never seen before in any neuron in any other species. Out now in
@sciencemagazine. Congrats Albert, Tim@mattlark@YiotaPoirazi & COhttps://science.sciencemag.org/content/367/6473/83 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Yangfan Peng proslijedio/la je Tweet
Are cortical excitatory synapses analog or discrete? Being able to analyze 1000’s of synapses from a proofread EM volume finds evidence for two states, one bigger than the other. 1st analysis paper from our EM data, led by
@sdorkenw,@SebastianSeung et al!https://www.biorxiv.org/content/10.1101/2019.12.29.890319v1 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Yangfan Peng proslijedio/la je Tweet
1/n Motor cortex controls the arm by sending neural activity patterns to the spinal cord and brainstem. But how are these patterns generated? We study this question in our new paper in
@nature, with J-Z Guo, J Cohen, M Mischiati,@AdamHantman, et al. https://go.nature.com/2tCjXFP pic.twitter.com/2bED3m1MGz
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Yangfan Peng proslijedio/la je Tweet
The end of the year can only mean one thing - it's The Spike's review of the year! “2019: a lightly bamboozled review of the year in neuroscience” by me Includes a high concentration of skepticism
@Neuro_Skeptichttps://link.medium.com/H7W5LtHVz2Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Yangfan Peng proslijedio/la je Tweet
Finally released! You can read here how we converted the yeast Pichia pastoris into an autotroph, growing on carbon dioxide.https://www.nature.com/articles/s41587-019-0363-0 …
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Yangfan Peng proslijedio/la je Tweet
Also out today in
@NatureNeuro : The@AllenInstitute tour de force measuring physiological responses of 60k neurons in mouse cortex to visual stimuli. One message: the responses of the vast majority of neurons can't be predicted using existing modelshttps://www.nature.com/articles/s41593-019-0550-9 …Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Yangfan Peng proslijedio/la je Tweet
Check out our latest preprint: https://www.biorxiv.org/content/10.1101/2019.12.13.876128v1 … "Distribution and strength of interlaminar synaptic connectivity in mouse primary visual cortex revealed by two-photon optogenetic stimulation."
#optogenetics#brainmapping@bakermind@timjarsky@lukecampagnolapic.twitter.com/AsbRjnDq58
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Very talented MD/PHD student
@FMittermaier in action
Excited about more human multipatch data
https://twitter.com/FMittermaier/status/1206649498480644104 …
0:20Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Yangfan Peng proslijedio/la je Tweet
"Structure and function of a neocortical synapse" https://www.biorxiv.org/content/10.1101/2019.12.13.875971v1 … This is a truly fascinating story about combining ephys with EM; spearheaded by Gregor Schuhknecht (
@GregorFPS) in Kevan Martin's lab at the Institut of Neuroinformatics in Zurich.Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Yangfan Peng proslijedio/la je Tweet
Exciting! Our new
@NatureBiotech manuscript on "The DNA of thing" https://www.nature.com/articles/s41587-019-0356-z … with my colleague Robert Grass and his team at@ETH_en! What's all about
?
A thread!


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4/4 We provide extensive documentation on all introduced optimizations. The low-cost Arduino-based pressure device can be assembled with minimal technical skill and used to upgrade existing setups with automated cleaning. This can also speed up training of novel patch-clamperspic.twitter.com/axPfXKwKP2
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3/4 We accomplished this by implementing the pipette cleaning protocol by
@craigrforest to our multipatch setups which allows clean2complete (red) to reuse failed patch pipette, while clean2extend (yellow) lets you probe additional synaptic connections with the same pipettes.pic.twitter.com/LuBqY79uJP
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2/4 We were able to detect 50 monosynaptic connections out of 150 probed connections in a single human cortical slice between 17 neurons. Over 600 synaptic connections can be probed in single patients. This will allow systematic analysis of the human microcircuit.pic.twitter.com/x23VdUeZfW
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Yangfan Peng proslijedio/la je Tweet
Dopamine modulates the size of striatal projection neuron ensembles https://biorxiv.org/cgi/content/short/865006v1 …
#biorxiv_neursciHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Discussing the latest dense EM connectome from the
@AllenInstitute with the smell of teargas in the room. That’s the scientific spirit
great @EITN_Paris meeting from the@HumanBrainProjpic.twitter.com/neNCfSaMI6
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Yangfan Peng proslijedio/la je Tweet
@rhira2016 has been exploring some of the@AllenInstitute connectivity data. He built a viewing tool: https://web.ece.ucsb.edu/~riichirohira/TopBM-2.06/index.html … (1) Position your cursor to set a seed location. (2) The map is the correlation of axonal projection patterns with the seed location. (1/4)pic.twitter.com/qVN5eo7ryiPrikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Yangfan Peng proslijedio/la je Tweet
I am looking for a senior research fellow/postdoc to join us in figuring out how Alzheimer‘s disease leads to neural system failure. Please get in touch if interested, and please RT. Thx!
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Yangfan Peng proslijedio/la je Tweet
About 50 people a year donate their living brain tissue to our Allen Institute for Brain Science for research.
@seattletimes reports, with incredible photos, on this work from the operating room to the lab.#brainscience https://www.seattletimes.com/pacific-nw-magazine/epilepsy-patient-gary-williams-donates-part-of-his-brain-to-science-while-he-and-his-healthy-tissue-is-still-alive/ … by@MikeSiegel7@SandiDoughtonPrikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi
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