An 8-week treatment with diet, exercise, and relaxation took an average of 2 years off subjects’ epigenetic age.https://www.aging-us.com/article/202913/text …
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not sure how I feel about this! (re: validation of epi clocks) I haven't read the paper but if they didn't already, would be interesting to see if the reversal reverts w/ 8 weeks of no diet/exercise etc, and if the rate of improvement slows with time
if you wanted to double down on absolutely confirming the validity of your epigenetic clock scheme in particular-- I imagine you'd design a study exactly like the one in the paper. multiple interventions, some very established, some brand new, no individual permutations tested
