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And if you manage to get one of them on your cap table but your startup starts to struggle, they'll divert their time and resources to grow companies that are doing well... A "shitty" sector focused Micro-VC will get their hands dirty and help out unlike the "top" funds in SF.
I have personal experience with the former. Putting that aside, this assumes you have the network to even get in front of Sequoia, Benchmark, Bessemer, etc. A lot of founders don't have that kind of access, ESPECIALLY if they are building in a city thats not NYC, BOS, or SF.
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