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A weird and potentially nasty pattern in biotech because of the incentives it generates: A company's assets are IPO'ed, VCs make a pile of money,but when taken to Phase III they flop (Stemcentrx, Unity, Sirtris).It may be obvious to bio veterans,but flops should be easier to spot
This is less true in practice than everyone outside of the industry suggests it is. Biopharm venture funds/new co creation funds aren’t dumbing in public markets, for most, this is just the start of the investment lifecycle. Functionally zero are knowingly playing hot potato
Theres always the hansonian effects, that 1 can meme oneself into thinking it actually works when a critical external observer may be - rosy about it. Idk honestly. As with many things I can only throw lots of time at this issue and post public predictions about wht IPOs wll fail
Agree this is complicated — but think it’s clear there should be more humility from those who’ve exited on products that failed to help patients. Keeps me up. If I’m ever in such a situation you two can hold me accountable for donating it all ;).
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