Why should the alternate approaches be inferior? Presumably if your main approach doesn't work the inferior approaches wouldn't work either. I always thought the alternate approaches should be more complex than the proposed one because unneccesary complexity is bad.
Reviewing NIH grants again (3x a year), here’s my NIH grantwriting tip #1: always include Potential Pitfalls/Alternative Approaches for each Aim, then briefly explain how you’ll dig yourself out of each pitfall and why the alternative approach is inferior to the one you proposed.
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The goal with describing alternative approaches is to inform reviewers that you’ve thought through attacking the scientific problem from different angles and ultimately chose the “best” one, which is the approach you’re ultimately proposing
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As an NIH reviewer I agree with this 100%. Another strategy is to own the potential pitfall and tell the reviewer what new information you may get and how it will inform your next experiments.
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Thanks for sharing. Not in the US though this is a useful tip for any grant application.
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So you basically evaluate the problem solving ability of the grant writer and their ability to find solutions. I worked before with a PI who had an NIH grant and he did have a great scope of his project.
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are you real? just few in your last selection?
Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi
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How many sentences for pitfalls for each aim do you prefer (ballpark)?
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Be brief, a sentence to introduce the pitfall and 1-2 sentences to address it. The goal is just to inform the reviewers that you’re thinking about your approach thoroughly and from different angles. This is part of the “scientific rigor” aspect the NIH tasks reviewers to evaluate
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