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JWeltner proslijedio/la je Tweet
Interesting phenomenon that also happens during development. ERV activation stimulates activation of ERV repressors
https://www.biorxiv.org/content/10.1101/2020.02.02.931501v1 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
JWeltner proslijedio/la je Tweet
Our new review/perspective on understanding the physical basis for phase separation of biomolecules is online today: https://annualreviews.org/doi/pdf/10.1146/annurev-biophys-121219-081629 … Although technically a review, we've used this to outline the contours of a general framework we've been working on for a while now.
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JWeltner proslijedio/la je Tweet
Brief summary of our recent paper: Rewiring of endogenous signaling pathways to genomic targets for therapeutic cell reprogramming https://doi.org/10.1038/s41467-020-14397-8 … Congratulations to my friend and former colleague Krzysztof Krawczyk!
#synbio#signaling#proteinengineering@ETH_BSSE (1)pic.twitter.com/sEe6w97w0p
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JWeltner proslijedio/la je Tweet
Our latest collaboration with Falco lab is out. Retinoic Acid brings
#ESC#pluripotency back to 2cell-like stage by tuning#Dux-#Duxbl1 expressionhttps://www.frontiersin.org/articles/10.3389/fcell.2019.00385/full …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
JWeltner proslijedio/la je TweetHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi
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JWeltner proslijedio/la je Tweet
This is a great paper from
@nevillesanjana group on the comparison head to head of WT Cas9, xCas9, Cas9-NG & a new variant xCas9-NG for KO, activation & repression in K562 cells. Unsurprisingly WT Cas9 outperforms PAM flexible variants. xCas9-NG is not bad https://www.biorxiv.org/content/10.1101/2020.01.22.916064v1 …pic.twitter.com/c2HZw2fPr4
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JWeltner proslijedio/la je Tweet
Our manuscript on the role of
#transposons in the evolution of#3DGenome is now out in@GenomeBiology: https://genomebiology.biomedcentral.com/articles/10.1186/s13059-019-1916-8 …@3D_Genome@4DNucleomePrikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
JWeltner proslijedio/la je Tweet
Here is my last work in the
@Trono_Lab! Dux is important for proper pre-implantation embryo development, but some murine zygotes can develop to healthy adults without it! https://dev.biologists.org/content/147/2/dev177725 …@Dev_journalHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
JWeltner proslijedio/la je Tweet
Heads up on Hui Yang, another potential aspiring CRISPR baby researcher https://ipscell.com/2020/01/heads-up-on-hui-yang-another-potential-aspiring-crispr-baby-researcher/ …pic.twitter.com/smygc4sVJJ
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JWeltner proslijedio/la je Tweet
Why not spend the long weekend reading a preprint on zinc finger gene evolution and their roles in TE silencing!https://www.biorxiv.org/content/10.1101/2020.01.17.910679v1 …
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Biologists say they need clearer guidelines on funding rules for this nascent field.https://ift.tt/377rOdk
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JWeltner proslijedio/la je Tweet
ISSCR statement on ethical standards for stem cell-based embryo models recognizes advances in the field and the scientific community's need to address these new challenges and to establish parameters for research. http://bit.ly/2R1c5a7
@dsrivastava_md@martinperaJAX#stemcellsHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
JWeltner proslijedio/la je Tweet
Work with human stem cells to create embryos is moving forward without ethical guidelines for oversight. A new paper underscores the issues and importance of developing them, globally
@StemCellReports https://www.cell.com/stem-cell-reports/fulltext/S2213-6711(19)30447-3?utm_medium=homepage …@CellPressNews by Insoo Hyun and colleaguespic.twitter.com/LpoI1pukmN
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Happy to share our preprint http://disq.us/t/3lbbzx4 on the requirement of Sox2 for the induction, maintenance and differentiation of naïve pluripotency. With
@Hstuart21@koo_lab@AliaksandraRPrikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
JWeltner proslijedio/la je Tweet
CRISPR-Cas13d induces efficient mRNA knock-down in animal embryos https://www.biorxiv.org/content/10.1101/2020.01.13.904763v1 … All right, first story from the Moreno-Mateos lab. A great collaboration with the
@BazziniLab . Do you wanna induce knock-down in zebrafish and other animal embryos? Take a look to it :)Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
JWeltner proslijedio/la je Tweet
Our new review has been accepted for publication.https://www.mdpi.com/2072-6694/12/1/183 …
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JWeltner proslijedio/la je Tweet
Exciting new research from
@astar_research explores NELFA as one of the earliest drivers of the 2C-like state in mouse embryonic#StemCellshttps://www.nature.com/articles/s41556-019-0453-8 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
JWeltner proslijedio/la je Tweet
SETDB1-mediated cell fate transition between 2C-like and
#pluripotent states. https://bit.ly/2QBR0m6 pic.twitter.com/Rs016fIJXA
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JWeltner proslijedio/la je Tweet
What happens when stem cells experience replication stress and activate ATR? They expand cell fate potential! Take a look at our first preprint: "ATR expands embryonic stem cell fate potential in response to replication stress"https://biorxiv.org/cgi/content/short/2020.01.01.888354v1 …
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JWeltner proslijedio/la je Tweet
First pub of the new year from the lab. "Recording mobile DNA in the gut microbiota using an Escherichia coli CRISPR-Cas spacer acquisition platform" The HGT data is pretty amazing to me even now. Led by
@c_munck &@raviusheth.https://www.nature.com/articles/s41467-019-14012-5 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi
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