The Loop on Twitter: "New study by @BenSessa @ProfDavidNutt @ProfValCurran @JacobSAday & Loop Director @FMeasham of @LivUni on role of pharmacology v environmental factors influencing ‘comedowns’ using medicinal or recreational MDMA:- https://t.co/OXjAK65MYM… https://t.co/ha0R8Oj4av"

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New study by @BenSessa @ProfDavidNutt @ProfValCurran @JacobSAday & Loop Director @FMeasham of @LivUni on role of pharmacology v environmental factors influencing ‘comedowns’ using medicinal or recreational MDMA:- https://journals.sagepub.com/doi/10.1177/02698811211055809 …https://twitter.com/bensessa/status/1484817246929268736 …

Dr Ben Sessa MBBS (MD) BSc MRCPsych @BenSessa

N=26 clinical MDMA sessions. Acute comedowns: 0 Affect drop in week after MDMA: 0 Compares favourably to frequent report of come downs & post-ecstasy affect drops seen in recreational use. Most likely factors: purity, dose, sleep and exercise