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William J. Greenleaf proslijedio/la je Tweet
Stoked to share our new
@sciencemagazine paper! We use stem cell-derived 3D#Organoids to track#chromatin dynamics across human forebrain development ~ with@jimena_andersen, Nasa,@PascaStanford@WJGreenleaf@HowardYChang@jkpritch & the whole team
https://science.sciencemag.org/content/367/6476/eaay1645 …pic.twitter.com/TvNEn4wMqC
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Our collaborative work with the Pasca lab mapping the chromatin accessibilty dynamics of human forebrain development just came out! Congrats to Alex, Nasa, and Jimena!https://science.sciencemag.org/content/367/6476/eaay1645 …
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Very excited our wonderful collaboration with the Das lab and Eterna on crowdsourced design of optimal molecular sensors is out on the BioRxiv!https://www.biorxiv.org/content/10.1101/2019.12.16.877183v1?rss=1 …
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William J. Greenleaf proslijedio/la je Tweet
Excited this is finally out!!! Great collaboration with Sandy Klemm, Lisa McGinnis,
@10xGenomics,@gracexyzheng,@HowardYChang, Ravi Majeti, and@WJGreenleaf. We utilized multi-omic single cell data to identify malignant regulatory signatures in mixed phenotype acute leukemia.https://twitter.com/NatureBiotech/status/1201627495138762752 …
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Our new paper on multiomic single cell analysis of leukemia is out in Nature Biotech: https://www.nature.com/articles/s41587-019-0332-7 …. Congrats to Jeff, Sandy, Lisa, and all co-authors!
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Wonderful collaboration with Zamore lab characterizing the sequence-specific binding and cleavage characteristics of Ago2 is now out in Molecular Cell. Congrats to Ben and Winston!https://www.cell.com/molecular-cell/fulltext/S1097-2765(19)30445-9 …
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William J. Greenleaf proslijedio/la je Tweet
HiChIRP allows a look at the role of lncRNAs in chromatin architecture. A modified 3C protocol paired with enrichment of RNA-associated chromosome conformation provides insight into the structures specific RNAs are involved in.
@HowardYChang@WJGreenleaf https://www.nature.com/articles/s41592-019-0407-x …pic.twitter.com/AY6awB7CpY
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William J. Greenleaf proslijedio/la je Tweet
Wonderful collaboration with Sandy Klemm, Lisa McGinnis,
@10xGenomics,@gracexyzheng,@HowardYChang, Ravi Majeti, and@WJGreenleaf. We utilized multi-omic single cell data to identify malignant regulatory signatures in mixed phenotype acute leukemia.https://www.biorxiv.org/content/10.1101/696328v1 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Our paper on multi-omic single cell data integration for understanding blood differentiation and molecular underpinnings of leukemia is now online on the BioRxiv!https://www.biorxiv.org/content/10.1101/696328v1 …
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Our productive collaboration with Herschlag and Das labs now out in PNAS:https://www.pnas.org/content/early/2019/04/03/1819047116 …
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Our work on high-throughput protein functional assays on a sequencing chip is out in Mol Cell! https://www.cell.com/molecular-cell/fulltext/S1097-2765(19)30130-3 … Congrats to Curtis and Peter!
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William J. Greenleaf proslijedio/la je Tweet
Our work on characterizing chromatin, methylation and structural variations (SVs) with a single nanopore sequencing assay on 4 human cell lines is up on bioRxiv (https://www.biorxiv.org/content/early/2018/12/22/504993 …)!
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William J. Greenleaf proslijedio/la je Tweet
Also see the pre-print by
@WJGreenleaf 's team (https://www.biorxiv.org/content/early/2018/12/22/504662 …) (our friendly competition) with a different take on applying nanopore sequencing to measuring chromatin accessibility.Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
William J. Greenleaf proslijedio/la je Tweet
Application of a PCA‐based correction method to >400 genome-wide
#CRISPR screens increases the power to detect co‐essential gene pairs & allows high‐resolution mapping of cancer cell networks --> http://bit.ly/2PMcxFf@WJGreenleaf@evaubo@Stanford@czbiohub#FunctionalGenomicspic.twitter.com/4iJHwQhCmf
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William J. Greenleaf proslijedio/la je Tweet
Position open for a motivated
#postdoc passionate about#chromatin architecture! I am starting a new lab at@RockefellerUniv to study how chromatin folding reflects & regulates genome function using#epigenomics &#biophysics tools. Details: https://riscalab.org/open-positions/ . Please RT.Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
William J. Greenleaf proslijedio/la je Tweet
In this week’s issue: mapping the chromatin landscape of human cancer, tracing the lineages of the mammalian gut community, and improving understanding of early vertebrate diversification https://scim.ag/2O6xObP pic.twitter.com/r9K7lAehgE
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Excited to be a part of the collaborative work out today in Science that maps chromatin accessibility in human cancer. Big congrats to
@doctorcorces and@JeffreyGranja!http://science.sciencemag.org/content/362/6413/eaav1898?fbclid=IwAR32ykH3iBbsrk4JEuanps2mthJZGuqmTCvbk2o8pHrmhvsUgGh8WNcPQbQ …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Nature news article on sequencer hacking is out! Special thanks to Jeffery Perkel for all his work covering this story!https://www.nature.com/articles/d41586-018-05769-8 …
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Our paper on methods for inferring gene networks from crispr screens has posted to bioRxiv:https://www.biorxiv.org/content/early/2018/07/16/369751 …
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