William J. Greenleaf

@WJGreenleaf

Associate Professor, Stanford University, Department of Genetics. Exploring the physical genome

Stanford U, Stanford CA
Vrijeme pridruživanja: srpanj 2011.

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  1. proslijedio/la je Tweet
    23. sij

    Stoked to share our new paper! We use stem cell-derived 3D to track dynamics across human forebrain development ~ with , Nasa, & the whole team 🙏

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  2. 23. sij

    Our collaborative work with the Pasca lab mapping the chromatin accessibilty dynamics of human forebrain development just came out! Congrats to Alex, Nasa, and Jimena!

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  3. 23. pro 2019.

    Very excited our wonderful collaboration with the Das lab and Eterna on crowdsourced design of optimal molecular sensors is out on the BioRxiv!

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  4. proslijedio/la je Tweet
    2. pro 2019.

    Excited this is finally out!!! Great collaboration with Sandy Klemm, Lisa McGinnis, , , , Ravi Majeti, and . We utilized multi-omic single cell data to identify malignant regulatory signatures in mixed phenotype acute leukemia.

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  5. 2. pro 2019.

    Our new paper on multiomic single cell analysis of leukemia is out in Nature Biotech: . Congrats to Jeff, Sandy, Lisa, and all co-authors!

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  6. 22. srp 2019.

    Wonderful collaboration with Zamore lab characterizing the sequence-specific binding and cleavage characteristics of Ago2 is now out in Molecular Cell. Congrats to Ben and Winston!

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  7. proslijedio/la je Tweet

    HiChIRP allows a look at the role of lncRNAs in chromatin architecture. A modified 3C protocol paired with enrichment of RNA-associated chromosome conformation provides insight into the structures specific RNAs are involved in.

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  8. proslijedio/la je Tweet
    9. srp 2019.

    Wonderful collaboration with Sandy Klemm, Lisa McGinnis, , , , Ravi Majeti, and . We utilized multi-omic single cell data to identify malignant regulatory signatures in mixed phenotype acute leukemia.

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  9. 9. srp 2019.

    Our paper on multi-omic single cell data integration for understanding blood differentiation and molecular underpinnings of leukemia is now online on the BioRxiv!

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  10. 27. svi 2019.
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  11. 8. tra 2019.

    Our productive collaboration with Herschlag and Das labs now out in PNAS:

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  12. 7. ožu 2019.

    Our work on high-throughput protein functional assays on a sequencing chip is out in Mol Cell! Congrats to Curtis and Peter!

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  13. proslijedio/la je Tweet
    22. pro 2018.

    Our work on characterizing chromatin, methylation and structural variations (SVs) with a single nanopore sequencing assay on 4 human cell lines is up on bioRxiv ()!

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  14. proslijedio/la je Tweet
    22. pro 2018.

    Also see the pre-print by 's team () (our friendly competition) with a different take on applying nanopore sequencing to measuring chromatin accessibility.

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  15. proslijedio/la je Tweet
    20. pro 2018.

    Application of a PCA‐based correction method to >400 genome-wide screens increases the power to detect co‐essential gene pairs & allows high‐resolution mapping of cancer cell networks -->

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  16. proslijedio/la je Tweet
    19. lis 2018.

    Position open for a motivated passionate about architecture! I am starting a new lab at to study how chromatin folding reflects & regulates genome function using & tools. Details: . Please RT.

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  17. proslijedio/la je Tweet

    In this week’s issue: mapping the chromatin landscape of human cancer, tracing the lineages of the mammalian gut community, and improving understanding of early vertebrate diversification

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  18. 26. lis 2018.

    Excited to be a part of the collaborative work out today in Science that maps chromatin accessibility in human cancer. Big congrats to and !

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  19. 24. srp 2018.

    Nature news article on sequencer hacking is out! Special thanks to Jeffery Perkel for all his work covering this story!

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  20. 16. srp 2018.

    Our paper on methods for inferring gene networks from crispr screens has posted to bioRxiv:

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