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Seems pretty useless to meditate much (aiming for real results) if one is very anxious or depressed. Sort of like running with mononucleosis. I've spent months in a rut, and now that I'm slowly just feeling better in general, my baseline keeps improving with minimal effort.
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To be fair, I did actually have a very bad bout of mono not so long ago. One downside of a culture convinced everything is personal and a "choice" is that it feels even worse when you're incapacitated.
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Calamity: "Oh fuck my health is fucked. Fuck." Resolution: Make the best of things, relax as much as possible. Heal slowly. Complication: "Shit I'm letting this person down, wow I'm not going anywhere with work, jeez I'm missing appointments. I suck what is wrong with me I-"