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  1. proslijedio/la je Tweet
    3. velj

    I thought to examine signal of natural evolution in by looking at distribution of mutations in the lineage leading to nCoV and compare this distribution to mutations occurring in other SARS-like bat viruses 1/9

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  2. proslijedio/la je Tweet
    Odgovor korisniku/ci

    This paper includes an early version of EPI_ISL_403928 from which contained numerous artefacts of the sequencing process. This was subsequently corrected and the current version shows no such divergence. Current analysis here:

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  3. proslijedio/la je Tweet
    1. velj

    Interesting report out of Japan. 210 nationals evacuated from Wuhan were tested; 2 were PCR+ but asymptomatic. No relevant contact hx.

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  4. 1. velj

    An interesting collection of masks on display 🧐

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  5. proslijedio/la je Tweet
    1. velj

    Important to recognise that antiviral immunity is not always durable. This happens in ; even with , reinfection with an identical virus can happen in volunteers

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  6. proslijedio/la je Tweet
    1. velj

    Please share far and wide: a free, open access, flexible research protocol for clinicians who want to run their own studies of nCoV2019. If we harmonise sampling globally we can combine independent work. The clinical characterisation protocol:

    Image showing tiers of recruitment intensity in a flexible observational research design
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  7. proslijedio/la je Tweet
    31. sij

    Sneezed on the train on the way home, muttered in Mandarin, and got a seat all the way. Amazing.

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  8. proslijedio/la je Tweet
    31. sij

    The NEJM article on asymptomatic transmission in Germany has had a rapid effect on policy. Fauci did a turn around the importance of asymptomatic transmission after its publication. Used as one justification for the new US travel restrictions.

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  9. proslijedio/la je Tweet
    31. sij

    We've updated analysis of transmission to compare with observed cases reported internationally, and estimate potential for outbreaks in new areas (assuming similar transmission to Wuhan). A full pre-print will be online shortly 1/

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  10. 29. sij

    ...”unlike patient 5, who was aged 10 and non-compliant to parental guidance...” patient 6 was aged 7, wore a surgical mask and didn’t get infected 😂

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  11. proslijedio/la je Tweet
    29. sij

    A new pneumococcal conjugate (PCV) made in India against the 10 most common serotypes causing disease in Africa & Asia: soon available for US$2 per dose! Can’t even imagine what a huge impact this will make on global pneumococcal disease!

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  12. proslijedio/la je Tweet
    29. sij

    Want to know about: - Changes in transmission over time for ? - The potential size and duration of the spillover event that started the outbreak? - Effectiveness of airport screening? Ongoing work by will be updated regularly here:

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  13. proslijedio/la je Tweet
    29. sij

    And so it would not be surprising if , or were among the first in Africa to see cases. Hopefully all the suspected cases will be negative.

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  14. proslijedio/la je Tweet
    29. sij

    Importation and Human-to-Human Transmission of a Novel Coronavirus in Vietnam | NEJM

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  15. proslijedio/la je Tweet
    28. sij

    A positive case of the novel coronavirus in Sri Lanka, and a suspected case in Côte d'Ivoire. I sound like a broken record, but these are the places of greatest concern given the potential public health resource constraints and subsequent risk of further transmission.

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  16. proslijedio/la je Tweet
    28. sij

    Lot of new plots appearing, but not always with underlying data. In case it’s useful, I’ve built an R package that can extract accurate underlying data from PDF plots:

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  17. proslijedio/la je Tweet
    27. sij

    Recently 2 cases of Group A streptococcus with reduced penicillin susceptibility and mutations in the penicillin binding protein 2x reported ( ). We looked to see how common mutations in GAS PBP2x and other PBPs are.

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  18. proslijedio/la je Tweet
    27. sij

    If you choose GP training in Yorkshire and the Humber, our new Trailblazer Training rotations offer an amazing opportunity to help tackle and learn about !

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  19. proslijedio/la je Tweet
    26. sij

    I just took 's list of 150 odd cases and made a histogram of the ages (suggestion by ). Does anyone have any thoughts on the paucity of pediatric cases or the peak around 40-50?

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  20. proslijedio/la je Tweet
    26. sij
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