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StuartBuck1's profile
Stuart Buck
Stuart Buck
Stuart Buck
@StuartBuck1

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Stuart Buck

@StuartBuck1

Vice President of Research, Laura and John Arnold Foundation. My album: http://amzn.to/1aUcJs4  My book: http://amzn.to/1f6Rl7U 

about.me/stuartbuck
Joined June 2011

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    Stuart Buck‏ @StuartBuck1 Jan 22

    Stuart Buck Retweeted Yevgeniy Feyman

    Medical journals are odd to me. Either they publish rigorous randomized trials or else simplistic correlation-is-causation stuff, but not as much that's in-between (such as regression discontinuity).https://twitter.com/YFeyman/status/1087778711477370882 …

    Stuart Buck added,

    Yevgeniy Feyman @YFeyman
    The new study (https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2720914 …) linking opioid marketing and mortality is interesting, but appears flawed in an important way. It's almost certain that drugmakers market to docs who are already likely to prescribe. 1/
    Show this thread
    8:04 PM - 22 Jan 2019
    • 10 Retweets
    • 94 Likes
    • Alexey Guzey Taylor Richards Daniel P. Moriarity Abigail Johnston Moon Watcher Michelle Caunca Joshua Goodman Catherine Maclean Ben Mundell
    11 replies 10 retweets 94 likes
      1. New conversation
      2. Dean Eckles‏ @deaneckles Jan 22
        Replying to @StuartBuck1

        Some even have guidelines that prevent being explicit about causal aims and conclusions without an RCT. @_MiguelHernan is good on this.

        1 reply 0 retweets 6 likes
      3. Stuart Buck‏ @StuartBuck1 Jan 23
        Replying to @deaneckles @_MiguelHernan

        Those guidelines are obviously wrong, but considering the quality and design of many non-RCTs in medical journals, it's probably good to avoid any mention of causation! :)

        0 replies 0 retweets 0 likes
      4. End of conversation
      1. New conversation
      2. Ali Jalali‏ @passerinebird Jan 23
        Replying to @StuartBuck1

        The authors don’t make any causal claims though... they’re pretty clear they’re only examining an association—An interesting association nevertheless, and argue for further study.

        1 reply 0 retweets 0 likes
      3. Stuart Buck‏ @StuartBuck1 Jan 24
        Replying to @passerinebird

        But then why end with the conclusion that policymakers should think about cracking down on marketing?

        1 reply 0 retweets 1 like
      4. Ali Jalali‏ @passerinebird Jan 24
        Replying to @StuartBuck1

        Seems like a sensible recommendation in either case. Whether it’s causal or pharma simply targeting physicians likely to prescribe, this is the most urgent public health crisis in decades. Isn’t a cautious approach better then wait and see?pic.twitter.com/uRUwqYkCru

        1 reply 0 retweets 0 likes
      5. 1 more reply
      1. New conversation
      2. Jennifer Doleac‏ @jenniferdoleac Jan 23
        Replying to @StuartBuck1

        Medical & public health journals are the final frontier for causal inference methods using observational data. I'm pretty sure those insights have reached all other disciplines by now.

        3 replies 3 retweets 23 likes
      3. 1 more reply
      1. mike johansen‏ @mikejohansen2 Jan 23
        Replying to @StuartBuck1

        Medical journals are odd in many ways beyond this point. Perhaps there could be a causal study looking at how incentives in publishing influence what gets published?

        0 replies 0 retweets 3 likes
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      1. Jon Huang‏ @jon_y_huang Jan 23
        Replying to @StuartBuck1

        Not so odd considering clinicians, and not epidemiologists or biostatisticians, run the show.

        0 replies 0 retweets 1 like
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      1. New conversation
      2. David Manheim‏ @davidmanheim Jan 24
        Replying to @StuartBuck1 @BenMundell

        I think appropriately, the journals would prefer analyses that present the data, where the fallacy of inferring causality is understood, rather than present analyses where their readers, and peer-reviewers, will not understand the potential shortcomings.

        1 reply 0 retweets 0 likes
      3. David Manheim‏ @davidmanheim Jan 24
        Replying to @davidmanheim @StuartBuck1 @BenMundell

        In part this is a failure of methodologists on both sides to allow a wider scope for their outreach and understanding, and in part a failure caused by stovepiping in academia.

        0 replies 0 retweets 1 like
      4. End of conversation
      1. Will Hulme‏ @wjchulme Jan 24
        Replying to @StuartBuck1

        Don't know if that's true or not but if so, I'd guess the denominator (medical studies) isn't much different?

        0 replies 0 retweets 0 likes
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      1. Andrew Althouse‏ @ADAlthousePhD Jan 24
        Replying to @StuartBuck1

        Yeah. It seems like J Clin Epi is where you have to go for that kind of stuff - it has clinical implications (so not purely *methods* work) but it’s a little too exotic for medical journals.

        0 replies 0 retweets 0 likes
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      1. Ance Tetere‏ @ancetetere Jan 23
        Replying to @StuartBuck1

        I so agree. -

        0 replies 0 retweets 0 likes
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      1. Ed‏ @edbritton83 Jan 23
        Replying to @StuartBuck1

        Rigorous science gives credibility. Crazy correlation causation stuff gives headlines. They need both.

        0 replies 0 retweets 0 likes
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      1. Kevin Denny‏ @KevinDenny Jan 23
        Replying to @StuartBuck1

        They have (re)discovered IV in the form of Mendelian randomization.

        0 replies 0 retweets 0 likes
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