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StevenSalzberg1's profile
Steven Salzberg
Steven Salzberg
Steven Salzberg
@StevenSalzberg1

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Steven Salzberg

@StevenSalzberg1

Bloomberg Distinguished Professor of BME, CS, and Biostats at Johns Hopkins University, tennis player, blogger at Forbes: http://forbes.com/sites/stevensa …

Maryland, USA
salzberg-lab.org
Joined August 2012

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    Steven Salzberg‏ @StevenSalzberg1 2 Aug 2020

    We don't have to wait months for phase 3 trials of #COVID19 vaccines to finish. We have safe vaccines already, and millions of people (including me) would take them now if permitted. Just do ithttps://www.forbes.com/sites/stevensalzberg/2020/08/02/start-vaccinating-now/ …

    4:45 AM - 2 Aug 2020
    • 268 Retweets
    • 745 Likes
    • Chhota Saifian Deathstroke🇿🇼 Faith Legazpi 🌤️🐙💖🏡 Cuidar al que Cuida Dan Rehab 4 Addiction Biaksiing Sophie Fuller Biberius Caldius Mero
    781 replies 268 retweets 745 likes
      1. Bazkie Bumpercar‏ @askdlfjasldkfj 2 Aug 2020
        Replying to @StevenSalzberg1

        I would be a bit more cautious. You can't say we have 'safe vaccines' if they're not tested extensively yet - I think you should rephrase that 'likely safe'. Vaccines only work if most people get vaccinated anyway, so I don't think it's useful to start right away.

        6 replies 6 retweets 96 likes
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      1. Tanja Maier‏ @tanjamaier17 2 Aug 2020
        Replying to @StevenSalzberg1

        Russia also has a vaccine developed with funding from its sovereign wealth fund and it’s already been tested on soldiers and govt officials with promising results. They expect to be able to offer vaccinations to Russians by Oct.https://www.google.at/amp/s/amp.dw.com/en/russia-plans-coronavirus-vaccination-program-from-october/a-54401689 …

        6 replies 3 retweets 11 likes
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      1. Brussels Pedestrian‏ @bXLpedestrian 2 Aug 2020
        Replying to @StevenSalzberg1

        We don't know that they are safe in all important respects yet. In particular, we don't know that they don't make infection by the virus *worse*, as can happen with some vaccine candidates, including I think one for SARS1.

        2 replies 0 retweets 30 likes
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      2. Logan J Everett‏ @loganjeverett 2 Aug 2020
        Replying to @StevenSalzberg1

        The claim that phase 3 is only about efficacy is simply false. Safety is still monitored in phase 3 and vaccines can still be rejected at this phase if too many adverse side effects are observed. Side effects that are very rare could be missed in the earlier, smaller phases.

        3 replies 11 retweets 157 likes
      3. Logan J Everett‏ @loganjeverett 2 Aug 2020
        Replying to @loganjeverett @StevenSalzberg1

        Part of what makes it ethical to give a candidate vaccine to thousands of people in phase 3 is that they are still being closely monitored for side effects and the study can be ended early if there are enough safety concerns. That won't be true if it's given out en masse.

        1 reply 4 retweets 81 likes
      4. End of conversation
      1. New conversation
      2. John P. Hussman, Ph.D.‏ @hussmanjp 2 Aug 2020
        Replying to @StevenSalzberg1

        With no phase 3, curious about thoughts regarding antibody-dependent enhancement, given that similar viruses such as SARS and MERS, as well as Dengue, Ebola, and possibly RSV can exploit weak neutralizing or non-neutralizing antibodies to amplify infectivity. My own concern here:pic.twitter.com/tNJU5GDCA1

        15 replies 34 retweets 172 likes
      3. Steven Salzberg‏ @StevenSalzberg1 2 Aug 2020
        Replying to @hussmanjp

        you are all misreading my article. Phase 3 is under way and I strongly support it for all vaccines. It will take 3 months or more. Until then, though, no one outside the trials can have the vaccines. I'm suggesting we re-think that.

        42 replies 1 retweet 24 likes
      4. Show replies
      1. peter kilmarx‏ @PeterKilmarx 2 Aug 2020
        Replying to @StevenSalzberg1

        Wrong and irresponsible. So far all we know is mRNA-1273 did not cause immediate side effects is 45 people. And mass manufacturing is already in the works.

        1 reply 3 retweets 28 likes
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      2. Logan J Everett‏ @loganjeverett 2 Aug 2020
        Replying to @StevenSalzberg1

        In addition to the safety concerns, there's another risk you ignore - that giving people a vaccine will influence their behavior towards more risk. How many people would start going out in public more after getting a vaccine with unknown efficacy?

        1 reply 8 retweets 87 likes
      3. Logan J Everett‏ @loganjeverett 2 Aug 2020
        Replying to @loganjeverett @StevenSalzberg1

        How many state govts would say "there's a vaccine now" and try to re-open, drop mask rules, etc if a vaccine becomes "available" even if the efficacy is unknown? Such outcomes would harm lots of people, including those who don't opt in themselves for the untested vaccine.

        2 replies 5 retweets 58 likes
      4. End of conversation

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