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My argument is that physical dependence/tolerance to opiods can and does develop on a timescale of days, under the claimed conditions
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I think that paper supports that?
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Tolerance to euphoric effects is distinct from withdrawal syndrome! The timescales are completely different!
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Euphoric effects diminish within hours, endogenous endorphin production effects (responsible for discontinuation syndrome) take days-weeks.
End of conversation
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. Banned in Sweden. SubGenius, Zhuangist, white-hat troll. Defrocked mathematician. Brain problems.