Oh this article is bull*shit*. Patients are more likely to continue using tramadol _precisely_ because it's considered less problematic than other opioids -- it's not more habituating, it's that doctors are less reluctant to prescribe it for chronic pain.https://www.upi.com/Health_News/2019/05/14/Study-Tramadol-carries-higher-risk-for-prolonged-use-than-other-opioids/2021557861143/?sl=1 …
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Here's the abstract -- p-hacking ahoy! This is a shitshow.https://www.bmj.com/content/365/bmj.l1849.abstract …
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"...risk of additional opioid use relative to people receiving other short acting opioids (incidence rate ratio 95% confidence interval 1.00 to 1.13; risk difference 0.5 percentage points; P=0.049)..." That's right, P = 0.049! Very wow, so science.
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You lead with a result like that, a klaxon should go off and a clown should drag you away in a huge net.
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Been on this stuff for over a decade because it works for spinal pain and is MUCH less addictive than opioids as Tramadol is the result of removing the Codeine from Ultracet.
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Ultracet = tramadol + acetaminophen. Tramadol is an opioid receptor agonist but has other activity (it hits a ton of other receptors) that also seems to contribute to pain relief.
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I started taking a low dose when I couldn't tolerate dopamine agonists any more. Will probably be on it the rest of my life. Not happy with that, but it beats living in torture.
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For sure!
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. Banned in Sweden. SubGenius, Zhuangist, white-hat troll. Defrocked mathematician. Brain problems.