Sjögren’s Expertise Center Groningen

@SjogrensUMCG

We focus on understanding and improving all things Sjögren’s syndrome! Bench to bedside. Part of Rheumatology & Clinical Immunology Department, UMCG.

Groningen, The Netherlands.
Vrijeme pridruživanja: ožujak 2018.

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  1. Our abatacept trial for primary s syndrome, out this week in new journal - not perhaps the results we were hoping for, but that's real research!

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  2. Take home message of our paper is that we cannot recommend abatacept treatment for amelioration of systemic Sjögren's syndrome disease activity, although improvements in ESSDAI and physician global disease activity were observed earlier with abatacept.

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  3. ...also many thanks to the multidisciplinary team that made this possible!

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  4. Good morning! We're proud to announce our Lancet Rheumatology article is online, examining the use of abatacept for treatment of early, active Sjögren's syndrome! Huge congratulations to first author for her years of dedication.

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  6. Germinal centers found in the salivary glands of Sjögren's patients are associated with more severe disease-but how do you define them histologically? Nakshbandi et al from kick off 2020 by suggesting you should use Bcl6!

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  7. Recruiting a 4 year post-doc! Project with Prof. Rob Coppes, Dr. Marco DeMaria and Dr. Sarah Pringle (all UMCG) using iPS cell technology and senolytics to rescue radiation induced SG damage - spread the word if you know anyone?

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  8. 2019 is nearly done! Time for the annual Christmas Brunch of the Sjögrens Syndrome research group 😋 From the eyes of Prof Kroese

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    4. pro 2019.

    Packed lecture theatre for this symposium in , showing just how much need there is for discussion about the side effects of checkpoint inhibitors!

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    28. stu 2019.

    Really chuffed this collaboration between ⁦⁩ and ⁦⁩ was fruitful and thought provoking

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  11. Are senescent epithelial progenitor and/or stem cells a common feature across inflammatory diseases? Wang et al have a first look in the intestines of patients with Crohn's disease

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  12. The is 1 of 3 sites in NL to have a proton irradiation facility! great promo video from funding body , featuring Prof. Coppes, explaining why this is so important

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  13. Honored that we received the Duncan A. Gordon award 2019 (highly influential research) for our publication 'B Cell Depletion Therapy Normalizes Circulating Follicular Th Cells in Primary Sjögren's Syndrome'

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    12. stu 2019.

    In patients with Sjogren's, Ianalumab, a dual-mode of action biologic combining BAFF receptor inhibition with B cell depletion, showed significant response in ESSDAI, a disease activity index, but did not seem to improve most PROs such as fatigue

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  15. Multiple SS-clinical trial results presented at . The challenge to identify responders remains! Lots of interest for our abatacept follow-up data (week 48) presented by Jolien!

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    10. stu 2019.

    Vaccinate your immune checkpoint inhibitor patients for flu and pneumonia! Urban legend that you have to avoid!

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  17. Great SSF study group meeting with interesting talks and Jolien receiving her abstract award! Well done!

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  18. And she’s done! Anniek van Roon, PhD, after her excellent thesis defense today: Raynaud s phenomenon - mirror of autoimmune disease 👍🏼

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  19. This week is the International Congress of Immunology, in Beijing, China. Here’s Xiaoyan Wang (PhD student), concentrating in the questions session after her oral presentation! She talked about senescent salivary gland progenitor cells in Sjögren’s syndrome - Well done!

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  20. Celebration Cakes! Department of Rheumatology and Clinical Immunology is a Center of Excellence in Rheumatology Research! Team work makes the dream work

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