Simon Currie

@SimonLCurrie

Postdoc in Mike Rosen’s lab studying molecular interactions and phase separation. PhD studying transcription factors in Barbara Graves’ lab .

Dallas, TX
Vrijeme pridruživanja: prosinac 2017.

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  1. proslijedio/la je Tweet
    2. velj

    How and Why to Build a Mathematical Model: A Case Study Using Prion Aggregation:

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  2. proslijedio/la je Tweet
    3. velj

    So have there been free-floating mitochondria in the blood all along, and we're just finally noticing them?

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  3. proslijedio/la je Tweet
    30. sij

    Cool study in this week's Science on the role of the endoplasmic reticulum in regulating P-Body formation and fission--a bit of stress granules in there too for the fans:

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    29. sij

    Our latest work, a collaboration with and lab, featuring a little data and a lot of thought from , now published in peer-reviewed form . Thread below

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    28. sij

    Liquidity Is a Critical Determinant for Selective Autophagy of Protein Condensates:

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    The Knowles group use a microfluidic system to demonstrate that liquid-liquid phase separated proteins found in biomolecular condensates can undergo a liquid to solid transition when subjected to shear stress |

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    26. sij

    Congrats my undergrads Shawn Rhyne, Tu Nguyen, Elizabeth Lieu on your first review paper!

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    24. sij
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    26. sij

    Enriching my reading list on RNA localisation and granules at Emma Linney presenting several endogenous live cell RNA visualisation methods in yeast from lab

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    25. sij

    Recruitment of mRNAs to P granules by condensation with intrinsically-disordered proteins. - PubMed - NCBI

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  11. proslijedio/la je Tweet
    24. sij

    O-GlcNAc Transferase Activity is Essential for RNA Pol II Pausing in a Human Cell-Free Transcription System

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  12. proslijedio/la je Tweet
    24. sij

    A nice review article: Integrative Structural Biology of Protein-RNA Complexes: Structure

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    24. sij

    Endorse. Chris is innovative, so much cool work to be done in his lab!!!

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  14. proslijedio/la je Tweet
    24. sij

    The cover story in features coach Kip Ioane's mission to nurture in athletes. Keep up the great work, coach: thanks for inspiring positive change!

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    23. sij

    Humbled and honored to spread the purpose and message of our program with the country courtesy of !

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    21. sij

    Specialisation of ribosomes in gonads through paralog-switching

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    22. sij

    interesting that diff. stresses are associated with changes in solubility for diff. sets of proteins, especially in light of recent work that suggests the entire proteome is oversaturated () - it will be exciting to figure out if/how this is regulated!

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  18. proslijedio/la je Tweet
    19. sij

    Very excited to share some of my PhD work in the Skd3 (human CLPB) is a potent mitochondrial protein disaggregase that is inactivated by 3-methylglutaconic aciduria-linked mutations 1/n

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  19. proslijedio/la je Tweet
    21. sij

    Very pleased to see our work come out today in PNAS. Led from the front by and involving many collaborators. Widespread remodeling of proteome solubility in response to different protein homeostasis stresses

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  20. proslijedio/la je Tweet
    19. sij

    Happy to share our new work on how prion and RNA-binding domains contribute to the formation of phase separated assemblies

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