Quick aside: Nobody knows HCQ works - antiviral/anti-inflammatory, they are all theories Zinc - I know the theory and its scientifically plausible but nobody knows the exact mechanism
-
Show this thread
-
This Tweet is unavailable.
-
This Tweet is unavailable.
-
Portugal Study Results: 77 (0.29%) of 26,815 C19 positive patients and 1,215 (0.36%) of 333,489 negative patients were chronically treated with HCQ (P=0.04) Conclusions: data suggest that chronic treatment with HCQ confer protection against C19 infectionhttps://www.medrxiv.org/content/10.1101/2020.06.26.20056507v1 …
5 replies 60 retweets 247 likesShow this thread -
And for you Zincophiles, there is a study showing that the addition of Zinc does indeed help over just HCQ+AZhttps://www.medrxiv.org/content/10.1101/2020.05.02.20080036v1 …
13 replies 89 retweets 360 likesShow this thread -
Negative Studies: This is the infamous VA retrospective study where the HCQ arm was significantly sicker This got huge headlineshttps://www.medrxiv.org/content/10.1101/2020.04.16.20065920v2 …
11 replies 24 retweets 170 likesShow this thread -
Gummi Bear Retweeted Dominique PERETTI
Then came the NEJM study where they 1) did a crazy propensity matching to align two arms which barely overlapped https://twitter.com/BranchWestyn/status/1258538499134742528?s=20 … 2) conflated intubation or death into a single outcome but didn't provide seperate numbers https://twitter.com/dperetti/status/1259154540630364162?s=20 … https://www.nejm.org/doi/full/10.1056/NEJMoa2012410?query=featured_home …
Gummi Bear added,
Dominique PERETTI @dperetti
Here is a thread about how the @nejm New York observational study was massaged in order to hide the significant benefit of Hydroxychloroquine (HCQ) for hospitalized patients that a closer look to data reveals. https://www.nejm.org/doi/full/10.1056/NEJMoa2012410?query=featured_home …Show this thread1 reply 40 retweets 199 likesShow this thread -
Then there was the Lancet study which was based on the implausible Surgisphere database compliments of Sapan S Desai, MD WHO recommended an end to HCQ use based on this study which later had to be retracted, because the data was allegedly fakehttps://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)31180-6/fulltext …
6 replies 65 retweets 296 likesShow this thread -
Gummi Bear Retweeted James Todaro, MD
The famous RECOVERY RCT trial which showed no benefit in late use. Around 25% died in There were however some strange dosing issues covered extensively by
@JamesTodaroMD https://twitter.com/JamesTodaroMD/status/1272661099985481733?s=20 … https://www.medrxiv.org/content/10.1101/2020.07.15.20151852v1 …Gummi Bear added,
James Todaro, MDVerified account @JamesTodaroMDUPDATE: France Soir releases part of the audio interview w/ Dr Martin Landray where he clearly bases HCQ dosing off treatment of amoebic dysentery (mentions it twice). Landray also mistakenly thinks the lethal dose of HCQ is 10 times 2400mg (24 grams!). https://youtu.be/31VEJlRyB2c https://twitter.com/JamesTodaroMD/status/1272542546758074369 …6 replies 31 retweets 205 likesShow this thread -
Overall, there are more positive than negative studies The negative studies are mostly about treating very sick patients with HCQ which is known not 2 work I believe there is some amount of bad faith involved here It has been 4 months and we do not have one proper RCT study...
11 replies 81 retweets 401 likesShow this thread
Loading seems to be taking a while.
Twitter may be over capacity or experiencing a momentary hiccup. Try again or visit Twitter Status for more information.