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  1. Prikvačeni tweet
    6. sij

    ! In the new January issue of Science : how PD-1 blockade may work differently than previously supposed; how common drugs, topical products cause contact ; all about mouth , and more to come:

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  2. A new study suggests that combining EGFR inhibitors and PD-1 checkpoint blockade could enhance the efficacy of against non-small cell lung :

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  3. 1. velj

    As tally of cases counted by rises, it’s worth reviewing what researchers learned from studying T and B cell responses in survivors of , including this 2017 paper by Zhao et al.

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  4. 30. sij

    Tipping the balance of T follicular helper cells in the body can lead to diseases like or exacerbate viral infection. researchers now have a better understanding of what regulates these elusive cells:

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  5. 29. sij

    In a new study, taking the "STING" out of human cell lines still preserved antiviral responses, thanks to a new sensing pathway directed by the protein DNA-PK:

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  6. 27. sij

    Scientists from have identified a responsible for controlling the activity of T follicular helper cells, a specialized subset of that assists B cell production of antibodies:

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  7. 27. sij

    . and fellow researchers have discovered a new DNA sensing pathway in human cells, but not mouse cells, that acts independently of the well-known DNA sensor, the protein STING, to defend against viruses:

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  8. 27. sij

    Science Immunology mourns the passing of Wendy Havran, a pioneering immunologist in the area of γδ T cell biology. Wendy was a founding member of our Advisory Board. “T-cell tracker” by was published by .

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  9. proslijedio/la je Tweet
    25. sij

    New in : Misawa, Beutler & colleagues from report that protein kinase D2 (Prkd2) is a T cell-intrinsic checkpoint, restraining TFH differentiation by limiting nuclear Bcl6. Loss-of-function Prkd2 mice have hyperactive B cells.

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  10. 24. sij

    Targeting a pathway controlling brush cell responses in mice helped prevent airway inflammation responses to common . Exploring this pathway might offer potential therapies for airborne , , scientists found:

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  11. 22. sij

    . and colleagues at , have discovered a novel pathway that coordinates inflammatory responses of chemical-sensing brush cells during exposure:

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  12. 22. sij

    A new study by the Chinese Academy of Sciences points to a possible trigger of cytokine release syndrome – a life-threatening condition that counteracts the success of :

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  13. 20. sij

    Messy cell death triggers the dangerous side of CAR T cell , found scientists from the Chinese Academy of Sciences:

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  14. 17. sij

    This week’s includes a profile of @NIAMS_NIH funded research in the January 3 issue of that identifies CD1a as a “molecular missing link” to understanding allergy to skin care products

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  15. 16. sij

    Interested in at ? Check out this paper from our November 2018 issue: a dynamic antibody duo -- for PD-1 and GITR -- may boost immunotherapy, reported scientists from :

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  16. 15. sij

    How does the body "remember” an ? What allows for allergies to persist throughout life? What controls the switch from "normal" to fatal allergic reactions, like ? A new study has answers:

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  17. 15. sij

    In collab with , - presenting this week at - published this study with us last May on an mRNA strategy for that may offer a faster and lower-cost option than the standard delivery of antibodies:

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  18. 15. sij

    . researchers have identified the expression factor BATF as a modulator of ILC2 fate into either tissue-resident or migratory populations:

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  19. 14. sij

    Check out this preclinical study by , reporting on a mRNA vaccine that prevented genital lesions in 100% of treated animals. The technology for this vaccine has been licensed to BioNTech, one of the presenters at this week:

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  20. 13. sij

    A new study shows the migratory subpopulation of group 2 innate lymphoid cells, critical defenders of barrier integrity, act as first responders to injury in mucosal sites like the lungs and the :

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  21. 13. sij

    . scientists now have greater insight into long-term persistence of allergic diseases, by identifying the source of the allergen-targeting IgE in the blood of mice and patients:

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