SchaferLabUMMS

@SchaferLabUMMS

Laboratory of Dori Schafer

Worcester, MA
Vrijeme pridruživanja: prosinac 2019.

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  1. proslijedio/la je Tweet
    27. sij

    . &co Synapse loss can occur early & prior to other -relevant pathology & is associated with synapse-localized complement C3. AAV approach to inhibit C3 protects synapses & preserves circuit function

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    21. sij

    We are so excited to share our new paper discussing a role for inflammatory cytokines in mediating local astrocyte‐dependent mechanisms of immune cell trafficking during neuroinflammation. Congrats to and Sindhu on a beautiful paper!

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  3. 26. pro 2019.

    Terrific research in collaboration with the labs of , Brian Popko, Stephen Crocker, Leif Havton, and Guangping Gao led by postdoc Sebastian Werneburg ()

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  4. 26. pro 2019.

    Our findings show that synapse loss occurs in human patients and precedes other pathologies in multiple animal models of demyelinating disease.

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  5. 26. pro 2019.

    Very excited that our work on how targeted complement inhibition blocks microglial synaptic engulfment and preserves circuit function in demyelinating disease is now out in !

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