Leif Erik Sander on Twitter: "Don't get me wrong, I believe that SARS-CoV-2 induced T cells afford (some level of) protection. Cross-reactive T cells are present in many people, but they can still get infected. Whether they positively impact the course of disease is currently under heavy investigation… https://t.co/DaeV3LkjN1"

@Sander_Lab

Infectious Diseases & Respiratory Medicine Physician @ChariteBerlin. The lab studies how #VaccinesWork & immunity to respiratory infections #STOPCOVID19

Berlin, Germany

Joined March 2018

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Martin Kulldorff‏ @MartinKulldorff 26 Sep 2020

Martin Kulldorff Retweeted Peter Staley

This is weird! @SWAtlasHoover stated the simple fact that immunity is higher than those with antibodies, whereupon Dr. Fauci criticizes him without contradicting what was actually said. Stating a simple scientific fact is not "extraordinarily inappropriate". What is going on?https://twitter.com/peterstaley/status/1309848839621423107 …

Martin Kulldorff added,

1:09

Peter StaleyVerified account @peterstaley

During my interview with Tony Fauci yesterday, I asked him about Scott Atlas's @SWAtlasHoover attempted takedown of @CDCDirector Redfield re how many Americans are still susceptible to #COVID19. Here's my question. /1 Full interview: https://www.instagram.com/tv/CFlEMt8Kg2B/?igshid=168osghuko3uw … pic.twitter.com/qTdATWdwrA

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256 replies 658 retweets 1,813 likes

Leif Erik Sander‏ @Sander_Lab 26 Sep 2020

Replying to @MartinKulldorff @SWAtlasHoover

Dear @MartinKulldorff Yes, we need open discourse. But the reports @SWAtlasHoover references (one of which we published) describe T cell cross-*reactivity* NOT cross-immunity. To equate cross-reactive T cells with immunity to SARS-CoV-2 is unfounded & simply false at this point

4 replies 3 retweets 34 likes

Martin Kulldorff‏ @MartinKulldorff 26 Sep 2020

Replying to @Sander_Lab @SWAtlasHoover

Thanks Lars Erik! You know more about this then I do. This KI paper seems to indicate that there is T-cell immunity after COVID19 infection. How should that be interpreted?https://www.cell.com/cell/fulltext/S0092-8674(20)31008-4 …

4 replies 5 retweets 52 likes

Leif Erik Sander‏ @Sander_Lab 26 Sep 2020

Replying to @MartinKulldorff @SWAtlasHoover

This is an important paper showing that most people exposed to SARS-CoV-2 develop T cells and antibodies that recognize the virus. They also found that some people w/o antibodies have T cell responses. But, the majority has both. It's unclear if T cells alone provide "immunity".

7 replies 0 retweets 7 likes

Leif Erik Sander‏ @Sander_Lab 26 Sep 2020

Replying to @Sander_Lab @MartinKulldorff @SWAtlasHoover

Moreover, he referred to "cross-immunity". That is not what this paper is about. The concept of x-protection is very exciting. We *hope* that pre-existing cross-reactivity may afford some level of protection. But it is unfounded to base public health policy on these findings.

2 replies 0 retweets 0 likes

Martin Kulldorff‏ @MartinKulldorff 26 Sep 2020

Replying to @Sander_Lab @SWAtlasHoover

Atlas mentioned T-cell immunity and cross-immunity as two different things, so you agree on that. Is the disagreement whether T-cell response after COVID19 infection leads to some form of immunity?

2 replies 0 retweets 5 likes

Leif Erik Sander‏ @Sander_Lab 26 Sep 2020

Replying to @MartinKulldorff @SWAtlasHoover

Don't get me wrong, I believe that SARS-CoV-2 induced T cells afford (some level of) protection. Cross-reactive T cells are present in many people, but they can still get infected. Whether they positively impact the course of disease is currently under heavy investigation

11:42 AM - 26 Sep 2020

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1 reply 0 retweets 5 likes

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