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14) 400,000 people die of malaria each year. It costs something like $5k to save one person from malaria, or $2b total per year. So if you want to save lives in the developing world, you can blow $2b a year just on malaria.

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15) And that’s just the start. If you look at the scale of funds spent on diseases, global warming, emerging technological risk, animal welfare, nuclear warfare safety, etc., you get numbers reaching into the trillions.

16) So at the very least, you should be using that as your baseline: and kelly tells you that when the backdrop is trillions of dollars, there’s essentially no risk aversion on the scale of thousands or millions.

17) Put another way: if you’re maximizing EV(log(W+$1,000,000,000,000)) and W is much less than a trillion, this is very similar to just maximizing EV(W).

18) Does this mean you should be willing to accept a significant chance of failing to do much good sometimes? Yes, it does. And that’s ok. If it was the right play in EV, sometimes you win and sometimes you lose.

19) And more generally, if you look at everyone contributing to the cause as one portfolio--which is certainly true from the perspective of the child dying from malaria--they aren’t worried about who it was that funded their safety.

20) So what does all this mean? It means that, when you’re thinking about your career, sometimes the altruistic thing to do is to take chances. Seek out the opportunities with the biggest upside, not the ones which are the safest, and hone in on that vision.

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21) Sometimes that means a startup, or an experimental field, or a bold play. Sometimes it means starting a charity or a movement. When it comes to the scales of money, better is bigger.

22) So given all that, why not bet all $100k? Why only $50k? Because if you bet $100k and lose, you can never bet again. And to the extent you think you have future ways to provide value that are contingent on having some amount of funding, it can be important to keep that.

4:19 AM · Dec 11, 2020Twitter Web App

23) So as we near the end of the year and you think about giving: think long-term and think big. If you can only give a little bit this year because everything else is helping you build out your career, that’s fine.

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24) Do what you can to maximize the amount you can give long term, even if you’re not sure how it will end.

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25) But if you’ve already made it--as many people who’ve held crypto this decade have--consider giving more than a little. Consider giving a lot. If there’s anything 2020 has taught us, it’s that the world needs it.

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