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Excited to share the preprint of my postdoc work w/
@sohallab in collab w/ Daniel Vogt & John Rubenstein We show that deletion of Tsc1, a gene associated with autism, causes somatostatin interneurons to express parvalbumin & adopt fast-spiking propertieshttps://www.biorxiv.org/content/10.1101/699892v1 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
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New work online! Transplanting interneuron stem cells rescues social behavior in PTEN mutant mice, but does so without fixing their abnormal inhibitory circuits. Led by Derek Southwell + s/o to
@Ruchimk and@HSeifikar!https://www.jneurosci.org/content/early/2020/01/27/JNEUROSCI.1063-19.2019 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
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Do you want to figure out how both active and passive head movements impact your primary visual cortex activity. Check out my first postdoc paper:https://www.biorxiv.org/content/10.1101/2020.01.20.913160v1 …
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Brains are amazing. Our lab demonstrates that single human layer 2/3 neurons can compute the XOR operation. Never seen before in any neuron in any other species. Out now in
@sciencemagazine. Congrats Albert, Tim@mattlark@YiotaPoirazi & COhttps://science.sciencemag.org/content/367/6473/83 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
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this is the maserati of slice rigshttps://twitter.com/YangfanPeng/status/1202973083386208256 …
0:06Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
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Being too self-centred can give rise to anxiety and depression. An effective antidote is to cultivate a sense of altruism, taking the whole of humanity into account. Appreciating the oneness of humanity leads us to recognise our essential equality as human beings.
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Before I heard of optogenetics, I was a mathematician simulating learning and oscillations in neural networks. Now my lab has a bunch of experimental data that demand new models. If you’re looking for postdoc opportunities modeling cortical dynamics please contact me!
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I wrote this up and posted. https://biorxiv.org/cgi/content/short/834895v1 … In some sense it is trivial, yet it is important. If you are using fluorescent reporters (GCAMP, dLight,....) and relating to behavioral events or neural activity, please read it and comment
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Tsc1 represses parvalbumin expression and fast-spiking properties in somatostatin lineage cortical interneurons http://disq.us/t/3jcvdv2 Tsc1 paper is officially published!!
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New work published: collaboration with
@DVogtLab and Rubenstein lab, led by@Ruchimk, showing that autism gene Tsc1 dynamically regulates PV expression and fast-spiking in SST interneurons well into adulthood!https://twitter.com/DVogtLab/status/1190282660528001024 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
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New paper from the lab in Neuron
@NeuroCellPress along-with a press release from@NIMHgov! Awake hippocampal-prefrontal replay for both spatial learning and memory-guided decision making. Reverse replay for learning from the past, and forward replay for planning future decisions.https://twitter.com/NIMHgov/status/1189560610985369600 …
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We knew that too much neural excitation is bad for circuit dynamics. Now a surprising link between neural excitation and longevity! Calm down, sleep well, and you'll live longer? Really cool stuff. Regulation of lifespan by neural excitation and RESThttps://www.nature.com/articles/s41586-019-1647-8 …
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3 years ago we asked what gamma oscillations do. In this new preprint,
@kathleencho shows that cross-hemispheric gamma synchrony is crucial for behavioral reappraisal:https://www.biorxiv.org/content/10.1101/784330v1 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
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1/ New in
@sciencemagazine w/@KarlDeisseroth lab: https://science.sciencemag.org/content/early/2019/07/17/science.aaw5202 …: new opsin + multi-photon holography to image ~4000 cells in 3D volumes over 5 cortical layers while also stimulating ~50 neurons to directly drive visual percepts; data analysis and theory reveal…pic.twitter.com/Wy1PLvrzz6
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A sensor for inhibitory transmission in the brain from our colleagues
@HHMIJaneliahttps://www.nature.com/articles/s41592-019-0471-2 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
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We are looking for Postdocs and Research Technicians to join us! Please spread the word to any bright, young scientists looking for an exciting postdoctoral research experience, and any motivated recent graduates looking for tech positions. http://www.bio.brandeis.edu/jadhavlab/position.html …
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Here is a link to a review/model of interneuron specification with Adam Kepecs for ARN. We describe an attractor model which we coin configurational code (as compared to combinatorial) , note similarity to Hopfield networks. Any and all feedback welcome.https://www.annualreviews.org/toc/neuro/forthcoming …
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New preprint out (collab w/ Dan Vogt & John Rubenstein): deficiency of the autism-associated gene Tsc1 causes somatostatin+ interneurons to express parvalbumin and fast-spiking properties. This change in phenotype remains reversible even into adulthood:https://www.biorxiv.org/content/10.1101/699892v1 …
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(1/n) Latest pre-print from lab! Octopi; open configurable high-throughput imaging platform. Led by an incredible graduate student
@hongquan_li - we crack puzzle of automated low-cost malaria diagnosis. Remember, malaria still kills ~1/2million people/year https://www.biorxiv.org/content/10.1101/684423v1 …pic.twitter.com/Yf3UWMyRHpPrikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi
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and
), helping rats learn from past decisions and plan where to go next: