Spectre/Meltdown nominated for most over hyped bug at Pwnies
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Nuking (all, not just BTB) branch prediction should also work (aside from meltdown I'm not aware of other ways speculation could be exploited, but not 100% sure) and seems likely to be possible with microcode.
If neither is possible, vendors should be offering compelling technical explanations of why it's not possible rather than refusing to even speak about it. The appearance is that they DON'T WANT TO FIX IT in any way that would look bad wrt performance.
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