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QD Clinic - Part 3 of my discussion of 2020 EULAR recommendations for RA treatment - this one addresses the use of MTX, GC & T2T. Watch on Youtube http://bit.ly/3bd8rln or Listen to the podcast http://bit.ly/382hEet 01:15 PM (CST)
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QD Clinic - Part 2 of my discussion of 2020 EULAR recommendations for RA treatment Watch on Youtube or http://bit.ly/2SoSe43 or Listen to the podcasthttp://bit.ly/2uoDha1
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Claims cohort study looked at serious infection in RA pts Rx w/ tofacitinib vs 7 biologics. Overall risk was 3.12/100PYs. Signif higher SIE in TOFA vs ETN (aHR 1·41), lower vs INFLX (0.81), similar to ABA, GOL, TCZ, ADA. TOFA 2X higher risk of Shingleshttp://bit.ly/36VO74x
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Tacrolimus as an option in RA? Metanalysis of 5 studies shows odds of achieving ACR20 was 1.71 (95% CI 1.20-2.42) for 1-2 mg/day and 2.30 (1.79-2.96) for 3 mg/day. Odds of creatinine elevation was 1.95 for 1-2 mg/day and 3.81 for 3mg/day. http://bit.ly/2v4Yrdl
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Wear a face mask to prevent others from catching whatever infection you have. It doesnt work to prevent you from getting the flu, Corona or chikungunya from otherspic.twitter.com/7HnEQCuG2p
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"Kites rise highest against the wind - not with it." - Winston Churchill
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QD Video - I discuss 2020 EULAR recommendations for RA treatment - Part I Watch on Youtube or http://bit.ly/2GUnoe0 or Listen to the podcasthttp://bit.ly/31q5idj
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Head drop - as a Sx of myopathy? 107 pts reviewed; 53% w/ specific Dx: Inflammatory myositis(n = 16), myopathy w/ rimmed vacuoles (10), radiation(8), nemaline ( 7), myofibrillar (4), facioscapulohumeral ( 3), 2 ea w/ incl. body,mitochondrial, PSS http://bit.ly/2RTFQdi
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"Mistakes are the portals of discovery." - James Joyce
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Danish Registry study of 12,185 Chronic Urticaria patients shows an overrepresentation mastocytosis and anaphylaxis, as well as atopic dermatitis, rheumatoid arthritis, SLE, thyroiditis and vitiligohttp://bit.ly/398gqP0
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Study of 368 SLE pts (1998 to 2012) found a high prevalence of epilepsy. Survey suggested epilepsy in 42% but evaluation found 36 (11.5%) w/ Sx, 83% w/ focal onset. Other manifestations of NPSLE in 50%, w/ 2-3 fold higher risk of CVA, psychosis & APS
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MRA vs FDG-PET in newly Dx GCA and Takayasus shows a differences in Sxs & imaging. Carotidynia & arm claudication more common in TAK with evidence of vascular inflammation (PET). GCA lesions by MRA showed more damage than inflammationhttp://bit.ly/394UCn6
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"We can't solve problems by using the same kind of thinking we used when we created them" -Albert Einstein
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The RheumNow Podcast is up! - Watch it here http://bit.ly/2UggBTU or listen to the podcast in the car, when you run or while folding clotheshttp://bit.ly/2RRTvkQ
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#UTSW Dr. Kermani - in GCA PET may be best at capturing Activity, while MRA may best define Extent of diseaseHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
QD Clinic - videos and podcast on patient care issues - this week: isolated inflammatory hip arthritis; monitoring vasculitis; mistakes in pain management; & when to use anakinra. Watch videos on http://RheumNow.com or listen by podcasthttp://bit.ly/2RQN2qG
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Swedish nationwide registers studied births in IIM/myositis pts betw 1973 - 2016 & found increased risk of caesarean section (aRR = 1.98), preterm birth ( 3.35) and low birth weight ( 5.69) AND incr risk of C-sections 1-3 yrs prior to the Dx of IIMhttp://bit.ly/38TvmAc
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"A lie gets halfway around the world before the truth has a chance to get its pants on". Winston Churchill
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CORRONA study of ~800 RA patients shows that high and low comorbidity scores and BMI status (obese BMI ≥ 30; n = 356 vs nonobese BMI < 30; n = 449) did not impair or alter the effectiveness of tocilizumab. http://bit.ly/38TExR6
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CORRONA study of ~800 RA patients shows that high and low comorbidity scores and BMI status (obese BMI ≥ 30; n = 356 vs nonobese BMI < 30; n = 449) did not impair or alter the effectiveness of tocilizumab.
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