Relative affinities for Rhinolophus sinica ACE-2 and human ACE-2 for four chimeric viruses encoding different spike receptor binding domains in an otherwise-constant bat SARSr-CoV genomic context (chimeras constructed in https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1006698 …). https://www.biorxiv.org/content/10.1101/2020.05.13.093658v1.full.pdf …
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Translate that more for public a tad...
WIV constructed a series of novel chimeric viruses encoding different receptor binding domains--with different receptor binding affinities--in an otherwise constant genomic context. And did so using "seamless ligation" procedures that leave no signatures of human manipulation.
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Nope. not yet. Thx.
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Reading between the lines, it means they likely did the same with the spike domain from the pangolin in the current CoV-2, adding the furin cleavage site. They will share that paper later, after the current situation settles. The greater world is not quite ready for it yet.
Thanks. Twitter will use this to make your timeline better. UndoUndo
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Not questioning your expertise nor credentials, but with respect, how do you know this?
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actually; this is the very origin of the Corana-19 Virus;!
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"All work with the infectious virus was performed under biosafety level 2 conditions"
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Can someone please point me towards the info that it was done under BL2 conditions i could not see it in the papers
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You are so smart! Thank you!
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And you can't say Richard has a political axe to grind. You will never find another person who hates Trump as much!
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