On TWiV 657, Shane Crotty suggested that there also seems to be a direct correlation btw pts' quant viral load and quant of AB titers seen at 6 mos; then, C.T. for PCR results may help to screen best convalescent plasma candidates more efficiently??https://youtu.be/xGW2IhFBlt8
Spot on @apoorva_nyc! From a COVID infectiousness point of view, maybe your qualitative (+/-) PCR is giving false pos, not that antigens are giving false neg. We need a Ct for PCR results! @CarlosdelRio7 @ADPaltiel @gregggonsalves @michaelmina_labhttps://www.nytimes.com/2020/08/29/health/coronavirus-testing.html …
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You are right to some extend but if more Viral load Via CT detected for longer period its important to screen off suitable convalescent plasma donor... I mean if we get repeated CT reading on 1st day of symptoms onset day... 5, day 8...
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qPCRs are giving false negatives, too...
Kiitos. Käytämme tätä aikajanasi parantamiseen. KumoaKumoa
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But re opening metrics are based on cases and positivity.. Surely a CT threshold should be set for using these metrics to drive such critical policy decisions?
Kiitos. Käytämme tätä aikajanasi parantamiseen. KumoaKumoa
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All reasonable viewpoints but testing is not performed in a clinical vacuum. This is where signs/symptoms and history of illness contextualize the laboratory result. I use the South Korea CDC guidelines as a framework.
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This was intended to regard mostly asymptomatic use of this test. If there are symptoms, then that is a whole different thing and symptoms usually take precedent over Ct b/c you have a symptom onset time/day to work with for individual and public health.
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I rather a false positive than a false negative. But someone can convince me otherwise....
Kiitos. Käytämme tätä aikajanasi parantamiseen. KumoaKumoa
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So, maybe or not?
Kiitos. Käytämme tätä aikajanasi parantamiseen. KumoaKumoa
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