is there any non-correlational evidence that obesity is unhealthy?
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(not intended as a vacuous hot take -- just visited my 80 yo grandma who has 100% clear mind and is still incredibly sharp, who goes swimming 2-3 times a week, and whose BMI for the last 20+ years has been hovering around 30)
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Replying to @alexeyguzey
Don’t want to sound offensive, but that’s a lot like “my grandpa smoked 2 packs a day and lived to 100”.:) that said I have nearly identical situation with my grandma (however a counterfactual is needed: maybe she would have been even stronger if she was leaner)
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Replying to @dsaava
sure, this is not strong evidence by itself; i just wanted to provide the context for how the idea appeared at all...
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Replying to @alexeyguzey @dsaava
The effect amongst older people isn't supposed to be very large, especially on a purely correlative basis, i.e., if you don't account for the history of smoking and pre-clinical weight loss.pic.twitter.com/wh6mQGAeyg
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(some excess weight is old age is proxy for not being sick from cancer or other major health problems, so it sort of signals good health even if it's probably not protective in and of itself)
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(Also, BMI is ultimately a proxy for what we really care about, i.e., adiposity and particularly visceral fat. People with higher BMIs because they have more bone and muscle mass aren't presumed to be at higher risk -- quite the contrary.)
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