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my favorite point that isn't just "lol git gud at probability" is that the most uncertainty by far in the drake equation is about the rate at which earth-like planets produce life; they argue for uncertainty over 200 orders of magnitude which is where the tail comes from
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Moreover, if those independent random variables were themselves roughly lognormally distributed, the posterior point estimates are just precision-weighted fractions of the observation. In other words, there is no particular reason to believe in a single "great filter".
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When we observe that the result of the Drake equation is lower than expected, no reason to expect it's because of just one term; we should probably just update our posterior on all of the terms downwards, each by a log factor proportional to the SD on its log prior.
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