Conversation

one way to say this is that "n-manifold" fundamentally includes n as part of the definition; the fact that invariance of domain lets you recover n from the underlying topological space for non-empty manifolds is a convenience but it obscures what's going on
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i actually know of no applications of allowing this. everywhere i’ve seen manifolds show up in other branches of math (most prominently in the neighborhood of the cobordism hypothesis, quantum topology, etc) we only ever consider n-manifolds for some n
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