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ProfDFrancis's profile
Prof Darrel Francis ☺ Mk CardioFellows Great Again
Prof Darrel Francis ☺ Mk CardioFellows Great Again
Prof Darrel Francis  ☺ Mk CardioFellows Great Again
@ProfDFrancis

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Prof Darrel Francis  ☺ Mk CardioFellows Great Again

@ProfDFrancis

Cardiologist, Scientist. I separate taking my work seriously (I do) vs myself seriously (I don't) Ideas my own (best ones stolen from my amazing PhD students)

London, England
inspirion.org/sc/aca~-MDQ9cX…
Joined November 2017

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    Prof Darrel Francis  ☺ Mk CardioFellows Great Again‏ @ProfDFrancis 28 Jul 2020

    Prize for the first person to spot what went wrong here. (First author is an old friend so I am sure she won't mind me pointing it out. Great study! All publicity is good publicity Valentina!)pic.twitter.com/pMMhP29NgB

    3:56 PM - 28 Jul 2020
    • 42 Retweets
    • 130 Likes
    • BenSerrand Niranjanan Nirmalananthan Edmundo E. Stan Kogan Golnaz Houshmand André Zimerman Ayaz Aghayev Ada Torres-Ramirez Muhammad Shariq Usman
    12 replies 42 retweets 130 likes
      1. New conversation
      2. Prof Darrel Francis  ☺ Mk CardioFellows Great Again‏ @ProfDFrancis 28 Jul 2020

        Bit tricky on that, so let me make it easier:pic.twitter.com/HECG91HWBg

        1 reply 1 retweet 7 likes
        Show this thread
      3. Prof Darrel Francis  ☺ Mk CardioFellows Great Again‏ @ProfDFrancis 28 Jul 2020

        Answer in the morning from @drgrahamcole who pointed it out to me.

        7 replies 1 retweet 3 likes
        Show this thread
      4. Prof Darrel Francis  ☺ Mk CardioFellows Great Again‏ @ProfDFrancis 28 Jul 2020

        OK I see some initial answers that are aimed at pretty high-brow analysis. You can ask F2 harrell about all that kind of fancy stuff. I am just looking at this.pic.twitter.com/Qp5DTPGErY

        2 replies 1 retweet 4 likes
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      5. Prof Darrel Francis  ☺ Mk CardioFellows Great Again‏ @ProfDFrancis 28 Jul 2020

        Hmmm... maybe people are finding this harder than I expected. A further hint here.

        1 reply 1 retweet 3 likes
        Show this thread
      6. Prof Darrel Francis  ☺ Mk CardioFellows Great Again‏ @ProfDFrancis 28 Jul 2020

        pic.twitter.com/xyqU2hsMsa

        1 reply 1 retweet 3 likes
        Show this thread
      7. Prof Darrel Francis  ☺ Mk CardioFellows Great Again‏ @ProfDFrancis 28 Jul 2020

        Why can we be *confident* that (a) what was described in the methods, was not was actually done and (b) that in one case, even what was done, was done incorrectly.pic.twitter.com/D79fNJL7GK

        8 replies 2 retweets 4 likes
        Show this thread
      8. Prof Darrel Francis  ☺ Mk CardioFellows Great Again‏ @ProfDFrancis 28 Jul 2020

        Lots of sophisticated answers overnight! But we are looking for something simple. Kishore is the closest to what Graham and I had in mind. Is that a good enough hint?pic.twitter.com/5wbPErcaHD

        1 reply 1 retweet 8 likes
        Show this thread
      9. Prof Darrel Francis  ☺ Mk CardioFellows Great Again‏ @ProfDFrancis 28 Jul 2020

        Step 1. Read this.pic.twitter.com/bpGdaaNK51

        2 replies 1 retweet 2 likes
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      10. Prof Darrel Francis  ☺ Mk CardioFellows Great Again‏ @ProfDFrancis 28 Jul 2020

        Step 2. Look at the top two rows of data and the bottom row.pic.twitter.com/zb3XDdIfEd

        1 reply 1 retweet 2 likes
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      11. Prof Darrel Francis  ☺ Mk CardioFellows Great Again‏ @ProfDFrancis 28 Jul 2020

        Now what jumps out and slaps you in the face? Remember that we said Kishore was close to the idea we are after.

        1 reply 1 retweet 3 likes
        Show this thread
      12. Prof Darrel Francis  ☺ Mk CardioFellows Great Again‏ @ProfDFrancis 28 Jul 2020

        Any doctor who has seen BNPs or CRPs or troponins should start laughing now. Hint. What do those three variables share, in your experience?

        3 replies 1 retweet 3 likes
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      13. Prof Darrel Francis  ☺ Mk CardioFellows Great Again‏ @ProfDFrancis 28 Jul 2020

        Excellent suggestion! Not the answer I was looking for, but getting at exactly the right issue.

        1 reply 0 retweets 3 likes
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      14. Prof Darrel Francis  ☺ Mk CardioFellows Great Again‏ @ProfDFrancis 28 Jul 2020

        Why do we sometimes report "median and interquartile range" rather than "mean and SD"?

        2 replies 1 retweet 4 likes
        Show this thread
      15. Prof Darrel Francis  ☺ Mk CardioFellows Great Again‏ @ProfDFrancis 28 Jul 2020

        The *two* leading answers are correct. Let's remind ourselves about Parametric and Non-parametric STATISTICAL TESTS. (@alexnowbar please make a note of this as a topic to cover specifically as people do find it a bit puzzling sometimes)

        1 reply 1 retweet 5 likes
        Show this thread
      16. Prof Darrel Francis  ☺ Mk CardioFellows Great Again‏ @ProfDFrancis 28 Jul 2020

        Suppose I want to describe to you the positions of ALL of the light blue pixels on this graph.pic.twitter.com/t8PO6v7qxK

        2 replies 0 retweets 2 likes
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      17. Prof Darrel Francis  ☺ Mk CardioFellows Great Again‏ @ProfDFrancis 28 Jul 2020

        It's easy. I would say: "Go to point (2, -1). Every pixel that is within 3 pixels of that point, is in my region of interest. Everything outside is not." How many numerical parameters do I need to describe the position of the light blue region?

        1 reply 0 retweets 1 like
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      18. Prof Darrel Francis  ☺ Mk CardioFellows Great Again‏ @ProfDFrancis 28 Jul 2020

        Hmmm... the answer "two" seems to be inexplicably popular, winning half the votes at the 6-vote stage. I can see how Donald Trump became president.

        2 replies 0 retweets 17 likes
        Show this thread
      19. Prof Darrel Francis  ☺ Mk CardioFellows Great Again‏ @ProfDFrancis 28 Jul 2020

        Here are the numbers I used. X coordinate of centre of circle, i.e. 2 Y coordinate of centre of circle, i.e. -1 Radius of circle, i.e. 3. How many numbers is that?

        1 reply 0 retweets 0 likes
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      20. Prof Darrel Francis  ☺ Mk CardioFellows Great Again‏ @ProfDFrancis 28 Jul 2020

        It occurs to me that some people were counting (2, -1) as a single numerical parameter. Anyway I am considering 2 and -1 to be separate numbers. (I can't believe I'm having to point this out)

        2 replies 0 retweets 3 likes
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      21. Prof Darrel Francis  ☺ Mk CardioFellows Great Again‏ @ProfDFrancis 28 Jul 2020

        Now look at this triangle. Think of all the ways you could describe the points of its interior. What is the smallest number of numerical parameters you can use?pic.twitter.com/tWlY5b4TDp

        1 reply 0 retweets 0 likes
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      22. Prof Darrel Francis  ☺ Mk CardioFellows Great Again‏ @ProfDFrancis 28 Jul 2020

        The picture itself uses 6 parameters. With those 6 parameters, 2 coordinates for each of the 3 corners, the triangle is described unambiguously, and uniquely - that is, only that exact triangle has those particular 6 values.

        1 reply 0 retweets 3 likes
        Show this thread
      23. Prof Darrel Francis  ☺ Mk CardioFellows Great Again‏ @ProfDFrancis 28 Jul 2020

        You could try a different combination, to try to cut down the wasteful usage of parameters. (Save the planet, etc) For example, how about: X and Y coords of point B, and then Orientation of one side (0 to 360 degrees) Orientation of other side (0 to 360 degrees) Seems to be 4?

        1 reply 0 retweets 1 like
        Show this thread
      24. Prof Darrel Francis  ☺ Mk CardioFellows Great Again‏ @ProfDFrancis 28 Jul 2020

        But no, if you only know the orientations, you don't know how far along the lines to put the points A and C. So you need X and Y coords of B, plus Orientation AND LENGTH of one side Orientation AND LENGTH of other side So that's 6 again. It turns out 6 is the minimum needed.

        2 replies 0 retweets 2 likes
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      25. Prof Darrel Francis  ☺ Mk CardioFellows Great Again‏ @ProfDFrancis 28 Jul 2020

        Now, how many numerical parameters would you need to correctly describe all the points inside this shape?pic.twitter.com/4Mzc2sOTKb

        2 replies 0 retweets 1 like
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      26. Prof Darrel Francis  ☺ Mk CardioFellows Great Again‏ @ProfDFrancis 28 Jul 2020

        Options

        1 reply 0 retweets 0 likes
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      27. Prof Darrel Francis  ☺ Mk CardioFellows Great Again‏ @ProfDFrancis 28 Jul 2020

        That's the problem we face in stats. The question we are asking in hypothesis testing is typically of this form: "These two groups of numbers, heights of men and heights of women. Could they easily be explained as one big group, with man versus woman being unrelated to height?"

        1 reply 0 retweets 5 likes
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      28. Prof Darrel Francis  ☺ Mk CardioFellows Great Again‏ @ProfDFrancis 28 Jul 2020

        The statistical hypotheis test, aka the P value, is telling us: "If in reality gender has no effect on height, how likely is it that when you measure heights of men and women, you would get a result as different as this between groups?"

        1 reply 2 retweets 6 likes
        Show this thread
      29. Prof Darrel Francis  ☺ Mk CardioFellows Great Again‏ @ProfDFrancis 28 Jul 2020

        To give you a P value, the stats test has to have a description of the data. It is really, really convenient if we can tell the stats test a simple description of the data. So suppose we have loads of data points:pic.twitter.com/LmEPzR7geD

        1 reply 0 retweets 4 likes
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      30. Prof Darrel Francis  ☺ Mk CardioFellows Great Again‏ @ProfDFrancis 28 Jul 2020

        Instead of feeding into the statistical test all the INDIVIDUAL data points, we just give it a SUMMARY of the distribution of the men, and of the women. The most convenient summary is when the data look reasonably "Normal" (Gaussian) in distribution.

        1 reply 0 retweets 4 likes
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      31. Prof Darrel Francis  ☺ Mk CardioFellows Great Again‏ @ProfDFrancis 28 Jul 2020

        Because then we can just say "In my sample, the men have height distributed with mean 70 inches, and standard deviation 5 inches. And the women have mean 65 inches, and standard deviation 5 inches." How many numerical PARAMETERS have we reduced our detailed graph to?

        1 reply 1 retweet 0 likes
        Show this thread
      32. Show replies

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