We are still far from figuring out how trees experience the world and how to translate that, but Vernor Vinge describes a whole space faring civilization of augmented trees (in A deepness in the sky)
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An immune response is an adaptation to a threat that happened enough times to allow a population of organisms to evolve a defense. A novel disease usually just kills the organism. We are the first industrial civilization that our single biosphere is being confronted with.
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