If thinkers hold on to fixed assumptions, they become subroutines in the virtual hivemind that comprehends the universe. Their followers are sub-subroutines. Most thinkers are doomed to explore infertile ground, due to an unquestioned decision made generations ago.
As always, confidence in belief must equal weight of evidence supporting the belief. Ideally we backtrack until we remove all priors. It is better to not seek the one correct belief but a weighted map of the space of possible beliefs.