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Plinz's profile
Joscha Bach
Joscha Bach
Joscha Bach
@Plinz

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Joscha Bach

@Plinz

FOLLOWS YOU. Artificial Intelligence, Cognitive Architectures, Computation. The goal is integrity, not conformity.

San Francisco, CA
bach.ai
Joined April 2009

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    Joscha Bach‏ @Plinz 2 Apr 2018
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    To build an intuition about how genes code for an organism, one may visualize that DNA is an operating system within each cell, which can only divide, differentiate, regulate or die. Individual genes can be thought of as rules for a cellular automaton on an emergent 3D lattice.

    7:56 PM - 2 Apr 2018 from Austin, TX
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    • Bravo 🐜🐻 corey Wouter Denayer Dan Garcia Erick Godsey Andrea Panno Sven Schmid “Hope in the Distance” Mayo Floeck
    1 reply 5 retweets 19 likes
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      2. Joscha Bach‏ @Plinz 3 Apr 2018
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        The grid emerges by adding new lattice locations at positions for new cells. Cells change state as a function of the state of their neighbors and their own state. (It is simplified, because the lattice gets frustrated by nonlocal interaction via hormones and axons etc)

        1 reply 1 retweet 1 like
      3. Joscha Bach‏ @Plinz 3 Apr 2018
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        Replying to @Plinz

        The automaton rule of the whole CA is your DNA (of which all cells have a copy)

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      4. End of conversation
      1. New conversation
      2. Rita J. King‏ @RitaJKing 2 Apr 2018
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        Replying to @Plinz

        What about epigenetic modification?

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      3. Joscha Bach‏ @Plinz 2 Apr 2018
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        Replying to @RitaJKing

        I think if it as flash memory, i.e. mutable state, whereas the DNA is ROM. Differentiation of cells within an organism is epigenetic, I think. Epigenetic modification is very important within organisms, but not much for inheritance between generations of organisms.

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      1. Joscha Bach‏ @Plinz 3 Apr 2018
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        Recording of local state is going to be mostly epigenetic, for instance via methylation, folding or chemical switches elsewhere in the cell.

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      1. Joscha Bach‏ @Plinz 3 Apr 2018
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        Yes, afaik the sequence of amino acids remains mostly unaffected. But it is not the point: the gene is a largely immutable subroutine, its activation state is a local parameterization.

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      1. Joscha Bach‏ @Plinz 3 Apr 2018
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        I suspect that almost all interactions are local. They are so ubiquitous that we don't think about them: "of course neighboring muscle cells will share a chemical context". Also, local interactions will look more uniform. The non local interactions are sparse, but draw attention.

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