just being in *any* study has psych effects on ppl that could be incorrectly ascribed to the treatment
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Replying to @elneurozorro @Plinz and
another example: due to being in a study eating habits may have changed, reducing symptoms
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Replying to @elneurozorro @Plinz and
pilot, case series studies are legit, esp for hard to treat conditions, RCTs come later.
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Replying to @puddleg @elneurozorro and
and press release/article says "compelling". Cannot be compelling. No control.
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Replying to @brain_apps @puddleg and
there is NO REASON not to collect data from a control group in this project.
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Replying to @brain_apps @puddleg and
the study had a control group of "20 age- and gender-matched neurotypical children without GI disorders were recruited." and is part of a series of studies they plan to make where for each one they control for other variables. The next one they're doing is controlling for placebo
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Replying to @ultimape @brain_apps and
Its right in the publication. I don't understand how you came to the conclusion you did about no control group. https://microbiomejournal.biomedcentral.com/articles/10.1186/s40168-016-0225-7 …pic.twitter.com/Y9OEUxJ4V4
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No PLACEBO control group. Makes results meaningless.
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Replying to @brain_apps @ultimape and
That would make most of the medical literature meaningless. Smoking would not be connected to cancer, as there is no placebo controlled trial.
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Completely different case. Smoking is a choice that damages health. ASDs are not a choice. Assessing treatment should be by RCT before in the public domain and require a placebo group.
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There are multiple ways of obtaining probability of causal effect, placebo control is a justifiable methodical preference but by no means the only way to obtain scientific results. What makes you personally so upset that you seem to misread the study?Something political?
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