The Game of Go has been explored for 2500 years and resulted in a body of theories that Go masters study in Go schools. Alpha Go discovered that human Go understanding was caught in a local optimum, and broke out of it. The game of modern physics started only 130 years ago...
The essay is very poorly reasoned, it would take some time to take it apart. In short, our hopes for success rest on the probable existence of a ground truth that sufficiently sustains the universal computations of a mind that has discovered the basic principle of epistemology.