Life expectancy is falling, and the Flynn effect is reversing. Both increased due to better nutrition, healthcare, and reduction of toxins (especially lead). Did we put something significant into our food, water or air to make it worse again?
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But it's not "thrown off regulation" that people die from. In developed countries They die from (1) tumors (2) stroke/infarction (3) traumas (see statistics). And (2) and partially (1) are caused by the abundance of food and inability of human beings to deal with it.
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Humans are trying their hardest to make food less digestible to insects in order to increase crop yields. Many of the same enzymes and enzymatic processes involved in digestion are conserved from insects to humans. GMOs can, and do, make food less digestible to humans.
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