The null hypothesis is the elaborate conspiracy theory that you happen to share with all your peers.
In practice, you rarely research properties that you are sure or you should fully expect to be unrelated.
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My point was, one can always start with some prior in a Bayesian fashion and update their beliefs as per the data.
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My point was that your prior must be informed by the previously existing evidence. For instance, if you don't have absolute evidence that vaccines cannot cause autism, your prior should be that some autism may be caused by vaccines and some may be not.
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