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Pinboard

@Pinboard

The light inside is broken, but I still work. The Cadillac of online bookmarking sites. Alleged nocoiner. http://pinboard.in  maciej@ceglowski.com +1 415 610 0231

Lonely street of broken dreams
pinboard.in
Joined July 2009

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    1. Pinboard‏ @Pinboard Apr 13

      What the covid shot taught me is that every time I've been really sick in my life, it was my immune reaction that was making me feel like death warmed over, not whatever innocent virus I had previously blamed. I feel so betrayed. Why *was* I hitting myself?

      3 replies 22 retweets 174 likes
      Show this thread
      Pinboard‏ @Pinboard Apr 13

      The human immune system needs a ground-up rewrite to better reflect the needs of stakeholders. There's a quarter billion years of technical debt in mammalian immune response and it shows in the crufty design. And don't even get me started on blood clotting. Disruptors needed!pic.twitter.com/n5eEV4bxdF

      8:52 AM - 13 Apr 2021
      • 19 Retweets
      • 95 Likes
      • Justin Lebar Ryan Galgon David L giulio rospigliosi John August tobin 🟡 Eric Lawrence 🎻 A. River
      4 replies 19 retweets 95 likes
        1. New conversation
        2. Pinboard‏ @Pinboard Apr 13

          If human immunological memory used blockchain we wouldn't need these booster shots

          5 replies 9 retweets 65 likes
          Show this thread
        3. Pinboard‏ @Pinboard Apr 13

          OMG somebody is out there using CRISPR to implement biological blockchain, aren't they? The idea is too stupid not to try and an uncontrollable plague of it will be a fitting end to our embarrassing civilization. Let's hope not enough is left for alien archaeologists to laugh at.

          3 replies 10 retweets 59 likes
          Show this thread
        4. End of conversation
        1. New conversation
        2. John Gordon‏ @jgordonshare Apr 13
          Replying to @Pinboard

          Cellular physiology is worse.

          1 reply 0 retweets 0 likes
        3. Watson Ladd‏ @WatsonLadd Apr 13
          Replying to @jgordonshare @Pinboard

          The Krebs cycle is elegant. FAA efficient. Glucolysis venerable, Rubisco, Terpenes flexible

          1 reply 0 retweets 0 likes
        4. Show replies
        1. Rahul Goma Phulore  💉 💉 🎉‏ @missingfaktor Apr 13
          Replying to @Pinboard

          Actually please do blood clotting! Would love to hear you rant about that.

          0 replies 0 retweets 0 likes
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        1. Paul Smith  💉 💉 🎉‏Verified account @paulsmith Apr 13
          Replying to @Pinboard

          yeah but just imagine the tedious HN thread “I could rewrite this in a weekend with React and CRISPR”

          0 replies 0 retweets 2 likes
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