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PeterHotez's profile
Prof Peter Hotez MD PhD
Prof Peter Hotez MD PhD
Prof Peter Hotez MD PhD
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@PeterHotez

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Prof Peter Hotez MD PhDVerified account

@PeterHotez

Vaccine Scientist-Author-Combat Antiscience @bcmhouston Professor Pediatrics Molecular Virology, @bcm_tropmed Dean, @TexasChildrens Chair in Tropical Pediatrics

Montrose, Houston TX
peterhotez.org
Joined May 2012

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    1. Prof Peter Hotez MD PhD‏Verified account @PeterHotez 6 Feb 2021

      1/10: My latest thinking after speaking with several important people on our current vaccine dilemma.

      107 replies 767 retweets 2,719 likes
      Show this thread
    2. Prof Peter Hotez MD PhD‏Verified account @PeterHotez 6 Feb 2021

      2/10: Right now, we just don't have sufficient vaccine supply to go around, and we need to clarify our goals. Later on as vaccine becomes available we can open it up to everyone but for now I think it helps to establish some national priorities.

      10 replies 113 retweets 1,056 likes
      Show this thread
    3. Prof Peter Hotez MD PhD‏Verified account @PeterHotez 6 Feb 2021

      3/10: Among the priorities: 1. Maximize reductions in hospitalizations and deaths, OR 2. Maximize reductions in community transmission, OR 3. Open the economy

      19 replies 107 retweets 995 likes
      Show this thread
    4. Prof Peter Hotez MD PhD‏Verified account @PeterHotez 6 Feb 2021

      4/10: While each reinforces the others, we still need to make some hard choices on what's most important to our nation. Also this needs to take into context, the horrible reality that the new variants are bearing down on us

      9 replies 78 retweets 869 likes
      Show this thread
    5. Prof Peter Hotez MD PhD‏Verified account @PeterHotez 6 Feb 2021

      5/10: Some like Mike Osterholm give us 6-14 weeks before the variants take over. In the meantime, news reports say that J&J and Novovax vaccines won't be here in the hundred million dose range until the summer, while mRNA in summer/fall.

      14 replies 123 retweets 861 likes
      Show this thread
    6. Prof Peter Hotez MD PhD‏Verified account @PeterHotez 6 Feb 2021

      6/10: Therefore, from my point of view, how do we best manage this from now until May.

      4 replies 70 retweets 717 likes
      Show this thread
    7. Prof Peter Hotez MD PhD‏Verified account @PeterHotez 6 Feb 2021

      7/10: Some are calling for single dose mRNA to spread it around. But my concern is that a single dose mRNA vaccine won't provide adequate or consistent virus neutralizing antibodies to protect against the new variants, whereas 2 doses look like some protection?

      16 replies 95 retweets 949 likes
      Show this thread
      Prof Peter Hotez MD PhD‏Verified account @PeterHotez 6 Feb 2021

      8/10: But this is squishy, some data would help. Alternatively, I understand we're sitting on tens of millions of doses of AZOx vaccine in the US? This was just authorized by the EMA for the EU. Even if it's not great for older populations, it could be released for 20-40 yos?

      11:58 AM - 6 Feb 2021
      • 124 Retweets
      • 1,127 Likes
      • Paula Doody Lauren L Witek Kathi Orgeron Lev Shmukler Alex. S. Tara Imani, AIA, ASID Lynda Mallinson second-class borough dweller Manish Vij
      32 replies 124 retweets 1,127 likes
        1. New conversation
        2. Prof Peter Hotez MD PhD‏Verified account @PeterHotez 6 Feb 2021

          9/10: This might free up more mRNA vaccine for older populations and also help with transmission reduction. Another possibility, create more particle or recombinant protein vaccines through DPA?

          7 replies 76 retweets 878 likes
          Show this thread
        3. Prof Peter Hotez MD PhD‏Verified account @PeterHotez 6 Feb 2021

          10/10: These are really tough decisions. I think the Biden Admin had a good plan in place for the nation to vaccinate by the fall, but now with the new variants looming we need to find a way to accelerate our national vaccination program.

          51 replies 202 retweets 1,632 likes
          Show this thread
        4. End of conversation
        1. New conversation
        2. Jenna Nober‏ @Jenna_Nober 6 Feb 2021
          Replying to @PeterHotez

          How can we stop spread without vaccinating younger people/kids?

          1 reply 0 retweets 4 likes
        3. Tina G‏ @TinaG_SD 7 Feb 2021
          Replying to @Jenna_Nober @PeterHotez

          We don't need to if the disease is reduced in severity to a moderate flu.

          0 replies 0 retweets 2 likes
        4. End of conversation
        1. RE Martin‏ @Mar1Edge 6 Feb 2021
          Replying to @PeterHotez

          Absolutely agree.

          0 replies 0 retweets 1 like
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        1. Jenna Nober‏ @Jenna_Nober 6 Feb 2021
          Replying to @PeterHotez

          Where is the urgency from FDA?

          0 replies 0 retweets 0 likes
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        1. lori parker-hartigan RN‏ @mamahartigan 6 Feb 2021
          Replying to @PeterHotez

          I’d be so grateful if my future daughter in laws , one with asthma,could get any vaccine soon. AZ sounds great. My sons, husband & I already fully vaccinated 🙏

          0 replies 0 retweets 4 likes
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        1. New conversation
        2. Dr. Yasser Aldhamen‏ @AldhamenYasser 6 Feb 2021
          Replying to @PeterHotez

          Another option is to start trials combining mRNA and viral-based vaccines. This will produce better efficacy (nAb + T cell immunity), and capacity too, since viral vectors can be easily scaled up (unlike mRNA and protein-based vaccines).

          1 reply 1 retweet 7 likes
        3. Dr. Yasser Aldhamen‏ @AldhamenYasser 6 Feb 2021
          Replying to @AldhamenYasser @PeterHotez

          https://www.nature.com/articles/d41586-021-00315-5 …

          0 replies 0 retweets 1 like
        4. End of conversation
        1. New conversation
        2. Louise Mensch‏Verified account @LouiseMensch 6 Feb 2021
          Replying to @PeterHotez

          This. Cuts onward transmissions by 67% immediately

          1 reply 1 retweet 11 likes
        3. M@L  😷 🇪🇺 🇬🇧 I'm with the 3.5% 😷‏ @malw77 6 Feb 2021
          Replying to @LouiseMensch @PeterHotez

          I've just had the AZ vaccine. The UK has approved it for all ages groups, and is not specifying under 65s. Second dose in 12 weeks. I was happy to have it because of the reduction in transmission rates.

          0 replies 1 retweet 6 likes
        4. End of conversation

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