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  1. Prikvačeni tweet
    3. ruj 2016.
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  2. proslijedio/la je Tweet
    4. velj

    Maize reticulons as receptors for autophagy-mediated ER turnover. New Plant Biology paper out now:

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    The Irish leaders’ debate is really quite shocking. The three leaders have a detailed grasp of complex welfare and tax issues, they are polite and courteous, they admit mistakes, they say sorry. They might even be largely honest. Why is all that possible in Ireland but not here?

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  4. prije 13 sati

    And mTor does a lot more than just control (some) cancers

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    New research shows that a membrane-bound organelle, the , contacts at least two membraneless compartments, P-bodies and stress granules, and influences their behavior. ($)

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  6. proslijedio/la je Tweet
    3. velj

    We have two Post-doctoral positions available using live imaging and /or genomics to investigate Notch regulatory dynamics. . Come join us!

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    Now I have a standard paragraph to sent to journal editors when I receive inquires 'does this paper have impact sufficient for the journal xxx?'. "First of all, before I give any comments, I should explain my standing regarding 'fit for the journal' notion. (cont)' 1/

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    1. velj

    The European Chemicals Agency has issued a notice saying that as the UK is now out of the EU it can no longer employ UK nationals. Welcome to the new world order

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    prije 23 sata

    Study claiming new coronavirus can be transmitted by people without symptoms was flawed: Authors didn't actually ask the patient if she felt any symptoms... Duh!!

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  10. prije 13 sati

    Nice interview of Levente Kovács , at

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    4. velj

    A fascinating thread on the science of the Coronavirus outbreak, following the trail of preprints. Demonstrates beautifully how science is done and why it works. Note that you’re seeing science being done in real time - not peer reviewed - some of the conclusions may be wrong.

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    CAIC is starting a monthly series of informal clinics for super-resolution fluorescence microscopy. Come along for advice on getting the most out of our SIM, STED and SMLM systems. First clinic is Friday 21st February - follow link for details

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    2. velj

    This day 140 years ago - 2 February 1880 - Charles Stewart Parnell became the fourth foreign politician in history to address the U.S. House of Representatives, saying: “Mr Speaker and gentlemen, the most pressing question in Ireland at the present moment is the tenure of land.”

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    1. velj
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    1. velj

    Direct visualization of degradation microcompartments at the ER membrane

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    Loss of ATG5-dependent autophagy —> NADH depletion and apoptosis. Death requires OxPhos/mito ATP synthase b/c NADH depletion leads to mito membrane depolarization. Autophagy prunes depolarized mito to stop death. stage 1 ? Sirtuins? Ac-coA? SARM1?

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  17. proslijedio/la je Tweet
    31. sij

    Really exciting new work in from the Voeltz lab revealing contact sites between the ER and membrane-less organelles including P-bodies. Expands our knowledge of inter-organelle crosstalk and its roles in RNA biology.

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  18. proslijedio/la je Tweet
    1. velj

    Our first preprint from the lab is out: promotes cell and organismal survival by maintaining pools. Six years of fun science, many dead ends and breakthroughs, fantastic collaborations all finally boiled down to a four-figure paper!

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  19. proslijedio/la je Tweet
    1. velj

    Molecular dynamics simulations reveal how the reticulon-homology domain of the autophagy receptor RETREG1/FAM134B remodels membranes for efficient selective reticulophagy

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  20. proslijedio/la je Tweet
    31. sij

    My dad grew up being told over and over again: “Money, power, business, titles, property... all can be taken away from you in an instant. The only thing nobody can ever take away from you is your education.” 6/n

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  21. proslijedio/la je Tweet
    1. velj

    Spontaneous Axonal ER Ca2+ Waves Mediate A Shift From Action Potential-Dependent to Independent Glutamate Release in the YAC128 HD-Model

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