Also check out the related News & Views, "Guardians of the learning gate" https://go.nature.com/33TcWNq pic.twitter.com/IrUvEILI5j
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Also check out the related News & Views, "Guardians of the learning gate" https://go.nature.com/33TcWNq pic.twitter.com/IrUvEILI5j
Outstanding work. However, how come the authors didn't perform the "final" test? Instead of showing impairment in learning via VIP photoinhibition, why not substituting the US teaching signal by VIP photoactivation? VIP photoactivation should promote learning, right?
Thanks! - and we did test this. Have a look at SFig 9. VIP photoactivation is not sufficient to induce associative learning. Which is actually not surprising: VIPs are mainly gating excitatory inputs to PNs, plus learning might additionally require neuromodulatory signals.
Amygdala: can't live with it, can't live without it
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