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A review on phase separation at the synapse by Mingjie Zhang and colleagues https://go.nature.com/2SbZTTf pic.twitter.com/5MJ9kJULaw
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Studies in mouse models of Pitt-Hopkins syndrome reveal impaired myelination and altered oligodendrocyte gene expression; this transcriptomic signature is shared in brains from individuals with
#autism spectrum disorder https://go.nature.com/2UmdZUw pic.twitter.com/W1wwd4E5S2
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A neural basis for tonic suppression of sodium appetite https://go.nature.com/2RBtqp3 pic.twitter.com/ZdccacbtHJ
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Whitening of odor representations, a computation that decorrelates activity for pattern classification by memory networks, by the wiring diagram of the
#olfactory bulb https://go.nature.com/2TFUczj pic.twitter.com/otJvzD86gz
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Lipid droplets accumulate in
#microglia with#aging in mouse and human brains; these cells are defective in phagocytosis, produce high levels of reactive oxygen species, and secrete proinflammatory cytokines https://go.nature.com/2vajSK8 pic.twitter.com/9j7VQzWWJj
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Shunting
#dopamine activity at the start of a reward-predicting cue prevents second-order conditioning without affecting blocking, indicating that cue-evoked transients function as temporal-difference prediction errors rather than reward predictions https://go.nature.com/2G8xFmv pic.twitter.com/hKK1C4nKWn
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A method for cell-type-specific drug-inducible protein synthesis inhibition using a combined knock-in mouse and chemogenetic approach https://go.nature.com/2tuT470 pic.twitter.com/lSixBuEXs7
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Investigation of the organization of the paraventricular nucleus of the
#thalamus (PVT) identifies two major classes of neurons that differ in terms of gene expression, anatomy, and function https://go.nature.com/2FOkVBp pic.twitter.com/oXNo0pnJNP
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Varying the timing of
#optogenetic manipulations in a Pavlovian task reveals a temporally restricted role of#dopamine neurons primarily in reinforcing stimulus–reward associations, and less related to directly generating movements https://go.nature.com/2uMk41T pic.twitter.com/KfahuTihYu
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Velocity cells in
#entorhinal cortex rescale after changes to the size and shape of the environment; head direction cells reorganize in an experience-dependent manner to align with the axis of environmental change https://go.nature.com/3a3Qo0x pic.twitter.com/yLqWGl0fQj
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De novo mutations identified by
#exome sequencing implicate rare missense variants in SLC6A1 in#schizophrenia https://go.nature.com/2QTk9JW pic.twitter.com/2fcIGH1wRV
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#Exome sequencing in#schizophrenia trios reveals only a small contribution towards overall risk from protein-coding de novo mutations https://go.nature.com/2ReYoD7 pic.twitter.com/ZqDccmW3VF
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Detailed 3D mapping of white matter pathways in the
#marmoset brain https://go.nature.com/2ssxLCu pic.twitter.com/FQQNzn9kEd
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While pursuing virtual prey, monkeys predict the prey’s upcoming movements, and neurons in the dorsal anterior cingulate cortex tracked prey position, velocity, and acceleration to facilitate these predictions https://go.nature.com/2Qt2ubx pic.twitter.com/wYtTCGc9Bl
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Latent dynamics in the neural
#manifold across three cortical areas in monkeys are stable throughout years of consistent behavior https://go.nature.com/35sIGt9 pic.twitter.com/mBlNUsAQFU
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@pgolshani and colleagues use a new wire-free#Miniscope to reveal instability of hippocampal place cells in epileptic mice; interneuron firing between CA1 and DG was also desynchronized https://go.nature.com/2QPOoQL pic.twitter.com/h8VoQZSraq
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Structures of virus-like capsids formed by the Drosophila neuronal Arc proteins https://go.nature.com/2QsPt1T pic.twitter.com/CWoJ4LIJr2
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Neurons in primate
#hippocampus non-linearly mix information about space and non-spatial elements of the environment in a task-dependent manner; this efficient code flexibly represents unique perceptual experiences and corresponding memories https://go.nature.com/2ZisOrF pic.twitter.com/TKicGRlCYE
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Our January issue is now live! https://go.nature.com/2saZPu3 pic.twitter.com/TrF73EKe54
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While Bayesian models provide good accounts of perceptual decisions, it is unclear how their components are represented in the brain. Here, the authors show that uncertainty decoded from visual cortex helps predict behavior. https://go.nature.com/2EOvPGO pic.twitter.com/p9lgLhz01q
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