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News, commentary and research coverage from the international monthly journal publishing the highest quality of work in all areas of neuroscience.

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Vrijeme pridruživanja: siječanj 2013.

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  1. Prikvačeni tweet

    Watch our animation on disease. It focuses on mechanisms whereby neurons become dysfunctional, how pathology develops, and touches on therapeutic strategies. Made with and produced with support from .

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  2. Everyone interested in a career in , is looking for an editor in clinical or systems neuroscience! Check it out!

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  3. A neural basis for tonic suppression of sodium appetite

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  4. Whitening of odor representations, a computation that decorrelates activity for pattern classification by memory networks, by the wiring diagram of the bulb

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  5. Lipid droplets accumulate in with in mouse and human brains; these cells are defective in phagocytosis, produce high levels of reactive oxygen species, and secrete proinflammatory cytokines

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  6. Shunting activity at the start of a reward-predicting cue prevents second-order conditioning without affecting blocking, indicating that cue-evoked transients function as temporal-difference prediction errors rather than reward predictions

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  7. proslijedio/la je Tweet
    21. sij

    Here is a News and Views from about 's recent paper on Arc capsids (). Written by Vivian Budnik and Travis Thomson:

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  8. A method for cell-type-specific drug-inducible protein synthesis inhibition using a combined knock-in mouse and chemogenetic approach

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  9. Investigation of the organization of the paraventricular nucleus of the (PVT) identifies two major classes of neurons that differ in terms of gene expression, anatomy, and function

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  10. Varying the timing of manipulations in a Pavlovian task reveals a temporally restricted role of neurons primarily in reinforcing stimulus–reward associations, and less related to directly generating movements

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  11. Velocity cells in cortex rescale after changes to the size and shape of the environment; head direction cells reorganize in an experience-dependent manner to align with the axis of environmental change

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  12. De novo mutations identified by sequencing implicate rare missense variants in SLC6A1 in

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  13. sequencing in trios reveals only a small contribution towards overall risk from protein-coding de novo mutations

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  14. proslijedio/la je Tweet

    Arc, a master regulator of synaptic plasticity, can mediate intercellular RNA transfer. Arc evolved from retrotransposon genes. A paper presents structures of retroviral-like Arc capsids as a basis to understand their function.

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  15. Detailed 3D mapping of white matter pathways in the brain

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  16. Congrats to our colleagues on a fantastic first issue! Check it out below.

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  17. While pursuing virtual prey, monkeys predict the prey’s upcoming movements, and neurons in the dorsal anterior cingulate cortex tracked prey position, velocity, and acceleration to facilitate these predictions

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  18. Latent dynamics in the neural across three cortical areas in monkeys are stable throughout years of consistent behavior

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  19. . and colleagues use a new wire-free to reveal instability of hippocampal place cells in epileptic mice; interneuron firing between CA1 and DG was also desynchronized

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  20. Structures of virus-like capsids formed by the Drosophila neuronal Arc proteins

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  21. We are saddened to hear of the passing of Bruce McEwen, a pioneer in stress research. Please enjoy his comprehensive 2015 review on this topic

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